Julho 2026 - Inventário do mês

Com atraso, mas aqui vai. Vide também no Substack

Versão esquemática de Mariana Barosa:

What multimorbidity shows us about guideline-driven evidence based medicine ou Sensible Medicine

TABELA DE CONTÉUDOS:

1. META-REVISÃO

2. REVISÕES SISTEMÁTICAS DE ENSAIOS CONTROLADOS E ALEATORIZADOS (ECAs)

3. ENSAIOS CONTROLADOS E ALEATORIZADOS (ECAs)

4. OBSERVACIONAIS

   1. Primários

5. OPINIÃO

   1. Perspectiva

6. FOAMed

Glossário:

✔ ✔ ✔ --> Muito relevante e reforça ou pode mudar a prática

? ? ? --> Muito relevante mas dúvidas

✗ ✗ ✗ --> Não eficaz mas muito relevante (contraria hipóteses e práticas ; valor didáctico ; etc.)

✔ --> Relevante e a favor da prática

? --> Relevante mas dúvidas

✗ --> Não eficaz mas relevante (contraria hipóteses e práticas ; valor didáctico ; etc.)

(sem símbolo) --> Pouco relevante (eventualmente interessante)

(sem símbolo) --> Não eficaz e pouco relevante (eventualmente interessante)

classificação pessoal, nem todos concordarão

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META-REVISÃO

Geral, Geriatria & Paliativos

? ? ? Safety of proton pump inhibitors: an overview of systematic reviews and meta-analyses | BMJ EBM

Meta-investigação & MBE

✔ ✔ ✔ Outcome switching in cohort studies of interventions: meta-epidemiological study | BMJ

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REVISÕES SISTEMÁTICAS de ECAs

tabela de conteúdos ↟

Geral, Geriatria & Paliativos

Calcium, vitamin D or combined supplementation to prevent fractures and falls: systematic review & meta-analysis| BMJ

Neurologia

✔ ✔ ✔ Effectiveness and tolerability of pharmacological prophylaxis for migraine headaches | BMJ EBM

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ENSAIOS CONTROLADOS E ALEATORIZADOS

tabela de conteúdos ↟

Cirurgia, Ortopedia & MFR

✔ ✔ ✔ Rivaroxaban Then Aspirin vs. Aspirin Alone after Total Hip or Knee Arthroplasty - EPCAT III | NEJM

✔ Prevention of Surgical Site Contamination with Cutibacterium acnes During Cardiac Surgery | JAMA Net Open

Dual mobility vs standard cups in total hip replacement for displaced femoral neck fractures - Duality | Lancet

? ? ? Robotic versus Open Pancreatoduodenectomy (PORTAL) | BMJ

Hematologia ✔ ✔ ✔ CT followed by ASCT vs nonmyeloablative consolidation: primary CNS lymphoma - IELSG43 | Lancet ✔ Continuous or Fixed-Duration Maintenance Therapy in Multiple Myeloma - ENDURANCE | NEJM

Infecciologia, Microbiologia & Antimicrobianos

✔ ✔ ✔ Temocillin vs carbapenems for bacteraemia due to 3GCephalosporin-res Enterobac - ASTARTÉ | Lancet

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ESTUDOS OBSERVACIONAIS

PRIMÁRIOS - SUB-ANÁLISE / COORTE / CASO-CONTROLO / INQUÉRITOS / A. ECONÓMICAS

tabela de conteúdos ↟

Doente crítico/urgente

Sudden Cardiac Death and its Relation to Previously Diagnosed or Occult Cardiac Disease at Autopsy | JACC

Sudden Cardiac Death Due to Myocardial Infarction w/ Obstructive and Nonobstructive Coronary Arteries | JACC

Infecciologia, Microbiologia & Antimicrobianos

✔ ✔ ✔ Routine serial follow-up blood cultures after a negative result within 48h of MSSA bacteremia | CID

✔ Time to Antibiotics and Mortality in Immunocompromised versus Non-Immunocompromised Patients | CID

Serum Albumin Level and Carbapenem on 30-Day Mortality in ESB+ E. coli and K. pneumoniae Bacteremia | CID

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OPINIÃO

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PERSPECTIVA

tabela de conteúdos ↟

Infecciologia, Microbiologia & Antimicrobianos

Procalcitonin—An Enigmatic Anxiolytic Biomarker | JAMA Network Open

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✔✔✔ FOAMed

tabela de conteúdos ↟

Cardiovascular

A Progressão Lenta de Onda R Nunca Teve a Evidência que Achávamos que Tinha | MBEDescomplicada

FA e ECAS | Cardiology Trials:

• Review of the SAFE-T Trial

• Review of the RACE II Trial

• Review of the PALLAS Trial

• Review of the EAST-AFNET 4 Trial

• Review of the AF-CHF Trial

Doente crítico/urgente

ChatCPR: AI’s Answer to the Question ‘When Will It Save Lives? | Sensible Medicine

TTL Tips 16: Ketamine in Trauma patients | St. Emlyn's

Geral, Geriatria & Paliativos

The Hubris of Screening for Disease -- Again | Sensible Medicine

“Doc, I got a MyChart alert that I am due for an RSV vaccine, can I get it today?" | Sensible Medicine

Drug-induced peripheral edema: a common, overlooked, reversible harm | TI

Hematologia

An Eagle Eye on AQUILA Survival Data. Our New Paper Is Out. IQWiG Wins, OpenEvidence Fails | Oncology Shot

Ferritin Levels – Redefining Normality in Women | Sensible Medicine

IA

Behind the Magic | Sensible Medicine

Infecciologia, Microbiologia & Antimicrobianos

Nirmatrelvir for Vaccinated or Unvaccinated Adult Outpatients with Covid-19 | Sensible Medicine

When doing more harms patients | Munro Report

Oral vs IV antibiotics | Therapeutics Initiative

Meta-investigação & MBE Should evidence come with an expiration date? | Sensible Medicine

“It’s in the new guidelines” does not always mean it’s time to change practice | Sensible Medicine

How to Keep up with the Medical Literature | Sensible Medicine For Hospital Medicine, the Answer Should Always be: Randomize | Sensible Medicine

The Trust the Evidence Scare Scale™ - Escala de receio do TTE ©

Neurologia

Improving how we prescribe zopiclone and trazodone for insomnia | Therapeutics Initiative

Deprescribing Cholinesterase Inhibitors: Good or bad idea? | TFP

Oncologia

Daraxonrasib in pancreas cancer | VPOT

POCUS

Difficult Airway Prediction | USGel

Psiquiatria

Escitalopram vs. citalopram: one enantiomer’s dominance reflects marketing, not evidence | Therapeutics Intitiative

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