Janeiro 23 - Inventário do mês

ARA - Aumento de Risco Absoluto | ECA - Ensaio clínico aleatorizado | ITA - Intention-to-treat Analysis | MA - Meta-análise | MBE - Medicina baseada na evidência | NIT - Non-inferiority trial | NNH - Number needed to harm | NNT - Number needed to treat | PPA - Per protocol analysis | RRA - Redução do Risco Absoluto | RS - Revisão Sistemática

REVISÕES SISTEMÁTICAS de ECAs

Cirurgia, Ortopedia & MFR

IA lidocaine vs IV sedation for closed reduction of acute anterior shoulder dislocation in the ED|CJEM

Doente crítico/urgente

Effect of Mobilization at 6 Months after Critical Illness | NEJM Evidence

Geral, Geriatria & Paliativos

Tramadol for knee or hip osteoarthritis | AC&R

Meta-investigação & MBE

Risk of Bias in RCTs of Transcatheter and Surgical Aortic Valve Replacement | JAMA Network Open

ENSAIOS CONTROLADOS E ALEATORIZADOS

Cardiovascular

Torsemide vs Furosemide after Discharge on Mortality in Hospitalized HF - TRANSFORM-HF | JAMA

Pulmonary Vein w/ Posterior Left Atrial Wall Isolation in Persistent AF - CAPLA | JAMA

Cirurgia, Ortopedia & MFR

Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture | NEJM

2 days versus 5 days of postoperative antibiotics for complex appendicitis - APPIC | Lancet

COVID-19

Fluvoxamine vs Placebo on Recovery in Outpatient Mild to Moderate COVID-19 - ACTIV-6 | JAMA

Visual-Olfactory Training for Patients With COVID-19 Resultant Olfactory Loss | JAMA OH&NS

Doente crítico/urgente

Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension | NEJM

Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest | NEJM

Fiber-Optic Intubation Among Resident Physicians After Higher- vs Lower-Fidelity Task Training | AA

Remifentanil vs Neuromuscular Blockers during RSI Among Patients at Risk of Aspiration | JAMA

Gastroenterologia & Hepatologia

Withdrawal of infliximab vs immunosuppressant in Crohn on combination - SPARE | LancetG&H

Geral, Geriatria & Paliativos

ML–Triggered Nudges on Serious Illness Conversations and End-of-Life Outcomes | JAMA Oncology

Infecciologia, Microbiologia & Antimicrobianos

Probiotic for pathogen-specific Staphylococcus aureus decolonisation in Thailand | Lancet Microbe

Nefrologia

Targeted-release budesonide for primary immunoglobulin A nephropathy - NefIgArd - Kidney Int

ORL

Self-treatment of Recurrent Benign Paroxysmal Positional Vertigo | JAMA Neurology

Técnicas, POCUS, Exames & Outros

MRI–Guided vs CT–Guided Stereotactic Body Radiotherapy for Prostate Cancer | JAMA Oncology

US in an impalpable tissue larynx model during a simulated front-of-neck access scenario | CEJM

Simulation-Based Training on Transesophageal Echocardiography - SIMULATOR | JAMA Cardiology

NORMAS DE ORIENTAÇÃO CLÍNICAS - GUIDELINES

Endocrinologia

Pharmacologic Treatment of Osteoporosis / Osteopenia - Living Clinical Guideline - ACP | AIM

Endocrine Society Hypercalcemia of Malignancy Guidelines | JAMA Oncology

Infecciologia, Microbiologia & Antimicrobianos

WHO fungal priority pathogens list to guide research, development and public health action

Nefrologia

Diabetes Management in CKD: Synopsis of the KDIGO 2022 Clinical Practice Guideline Update | AIM

ESTUDOS OBSERVACIONAIS

RS COM ESTUDOS OBSERVACIONAIS (com ou sem ECA)

Doente crítico/urgente

Safety Outcomes of Direct Discharge Home From ICUs | Critical Care Medicine

Endocrinologia

Treatments to Prevent Fractures in People With Low Bone Mass or Primary Osteoporosis | AIM

Infecciologia, Microbiologia & Antimicrobianos

Synovial Fluid and Serum Neutrophil-to-Lymphocyte Ratio for Native Septic Arthritis in Adults | BJSA

Acute Bacterial Infectious Conjunctivitis? | Rational Clinical Examination Systematic Review - JAMA

SUB-ANÁLISES DE ECAs

Cardiovascular

Mavacamten on Cardiopulmonary Exercise Testing - EXPLORER-HCM, Prespecified | JAMA Cardiology

Restoring mortality data in the FOURIER CVOT of evolocumab in patients with CVD | BMJ Open

Frailty and Multidomain Physical Rehabilitation in Elderly with Acute HF - REHAB | JAMA Cardiology

Doente crítico/urgente

Calcium in OHCA-PEA w/ Hyperkalemia-like or Ischemia-like EKG characteristics - COCA|Resuscitation

COORTE, CASO-CONTROLO & COORTE TRANSVERSAL

Cardiovascular

High-dose nitroglycerin infusion in sympathetic crashing acute pulmonary edema | AJEM

High sensitivity troponin – Six hours is the magic number | AJEM

Cirurgia, Ortopedia & MFR

Hemicolectomy vs appendectomy for appendiceal neuroendocrine tumours 1–2 cm in size | LancetO

Many Surgical Patients Might Not Need Pharmacologic VTE Prophylaxis | Annals of surgery

Doente crítico/urgente

Effectiveness of Amiodarone and Lidocaine for In-Hospital Cardiac Arrest (IHCA) treatment | Chest

Alcohol Withdrawal – Should We Reach For Phenobarbital? | AmJRCCM

Endocrinologia

SGLT2i vs DPP4i Inhibitor and Obstructive Airway Disease and Exacerbation | JAMA Network Open

Home Waking Salivary Cortisone to Screen for Adrenal Insufficiency | NEJM Evidence

Geral, Geriatria & Paliativos

Postoperative Restrictive Opioidand changes in prescribing and Chronic Use | JAMA Oncology

Hematologia

EBV Viral Load Monitoring Strategy and the Risk for PTLD in Adult Liver Transplantation | AIM

Imuno-mediadas

Hydroxychloroquine Dose and Risk for Incident Retinopathy | AIM

Infecciologia, Microbiologia & Antimicrobianos

Regional Antibiotic Delivery for Implanted Cardiovascular Electronic Device Infections | JACC

When Should MRSA Coverage Be Considered in Empiric Antibiotic Therapy for CAP? | AAC

Neurologia

Endovascular Brain-Computer Interface for Severe Paralysis in 4 Patients - SWITCH | JAMA Neurology

IV Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of DOACs | JAMA Neurology

Atrial Fibrillation Assessment after Embolic Stroke of Undetermined Source | Annals of Neurology

Oncologia

Osteoradionecrosis of the Jaw Following Proton Radiation Therapy for Head&Neck Cancer|JAMAOHN

Técnicas, POCUS, Exames & Outros

POCUS compression of the carotid artery for pulse determination in CPR | Resuscitation

Sensitivity of modern multisliceCT for SAH after headache onset: a 10-year analysis | EMJ

INQUÉRITOS / QUALITATIVOS

Geral, Geriatria & Paliativos

Analysis of Unmet Information Needs Among Patients With Thyroid Cancer | JAMA OH&NS

Meta-investigação & MBE

Financial conflicts of interest among US authors of 2020 clinical practice guidelines | BMJ Open

ANÁLISE ECONÓMICA

Cardiovascular

Anticoagulant Therapy for Cancer-Associated Thrombosis - Cost-effectiveness Analysis | AIM

Cirurgia, Ortopedia & MFR

Novel Macrophage-Regulating Treatment for Wound Healing in Diabetic Foot Ulcers | JAMA NO

Cost-effectiveness of Laparoscopic vs Open Gastrectomy for Gastric Cancer | JAMA Surgery

Laparoscopia ligeiramente mais cara (com QALYs iguais), mas a diferença a 1-ano foi mínima.

CASO CLÍNICO / IMAGEM CLÍNICA

Cardiovascular

Bilateral Subclavian Artery Stenosis Presenting as Refractory Hypotension | AIM

Cirurgia, Ortopedia & MFR

Gigantic Unruptured Abdominal Aneurysm Successfully Treated w/ Endovascular Repair (EVAR) | AIM

Endocrinologia

Symptomatic Calcification in a Patient With Normophosphatemic Tumoral Calcinosis | AIM

Scurvy's Systemic Clinical Picture: A Multiorgan Presentation of a Conspicuous Disease | AIM

Gastroenterologia & Hepatologia

Case of Ibuprofen-Induced Liver Injury | AIM

Medical Management of Emphysematous Gastritis | AIM

Cholecystalgia: Atypical Presentation of Congestive HF in Alcohol-Induced Cardiomyopathy | AIM

Hematologia

A Tale of Two Hematological Malignancies: CML Followed by CLL in the Same Patient | AIM

Imuno-mediadas

Dermatomyositis Presenting as Pseudo-angioedema | AIM

Immune Checkpoint Inhibitor-Induced Polyarthritis: A Case Series | AIM

Renal Sarcoidosis Presenting as Fanconi Syndrome

Infecciologia, Microbiologia & Antimicrobianos

Atypical Presentation of PML with Newly Diagnosed HIV Infection | AIM

Neurologia

Floccillation: A Diagnostic Clue to Delirium | AIM

Oncologia

Puzzling Case of Rapidly Progressive Global CNS Deterioration From IVLCL(DLBC) | AIM

OPINIÃO

REVISÃO NÃO-SISTEMÁTICA / NARRATIVA

Infecciologia, Microbiologia & Antimicrobianos

Management of Latent Tuberculosis Infection | JAMA

Neurologia

Migraine | Annals of Internal Medicine

Management of chronic migraine | The BMJ

PERSPECTIVA

Infecciologia, Microbiologia & Antimicrobianos

On the Rise, Candida auris Outwits Treatments and Travels Incognito in Health Care Settings | JAMA

Twenty-Strain “Universal” mRNA Flu Vaccine Effective in Animal Studies | JAMA

Neurologia

Lecanemab Linked to Death in AD Patient With Stroke Given tPA - Medscape / NEJM

Oncologia

Updated Labeling for Capecitabine, a 25-Year-Old Cancer Drug | JAMA

FOAMed

Cardiovascular

Atrial Fibrillation: Gray Matters Segment | Core IM Podcast

SGEM#388: It Makes No Difference Now - CCB or BB for AF w/ RVR in HFrEF - The SGEM

Doente crítico/urgente

Adult CXR Cases 028 • LITFL • CMC Radiology

Endocrinologia

#377 Adrenal Incidentalomas with Dr. William Young - The Curbsiders

Geral, Geriatria & Paliativos

#331 - Top 5 Tools for Practice of 2022 - Tools for practice

Infecciologia, Microbiologia & Antimicrobianos

Five Things Pharmacists Should Know About Ventilator Associated Pneumonia (VAP) | IDS

Nefrologia

PulmCrit – Myth-busting the conditional nephrotoxicity of piperacillin-tazobactam

Neurologia

#375 Delirium in the Hospital featuring Dr. Esther Oh - The Curbsiders

#370 Parkinson’s Disease for Primary Care with Dr. Albert Hung - The Curbsiders