2021 - Novembro

ECA - Ensaio clínico aleatorizado | MBE - Medicina baseada na evidência | RS - Revisão Sistemática

RS de ECA

• Cardiologia

  • Ivabradine in HF

  • PCI vs CABG in LMCAD: an individual patient data meta-analysis | JW

  • Pretreatment With Oral P2Y12 Inhibitors in Patients With NSTEACS

  • Lowering BP w/ ACEi/ARB Reduced Risk for New-Onset Diabetes

  • Hit or miss: the new cholesterol targets

• Hematologia

  • Risk of Infection Associated With Administration of Intravenous Iron

• Neurologia

  • Thrombectomy for anterior circulation stroke beyond 6h (AURORA)

  • Intensive vs Standard BP Reduction: Cognitive Decline and Dementia

• ORL

  • Interventions for Menière’s disease: an umbrella systematic review

• Ortopedia & MFR

  • Time to Benefit Bisphosphonate - Postmenopausal Women w/ Osteoporosis

ECA

• Cardiologia

  • QFR-PCI vs standard angiography

  • FFR-PCI vs. CABG

  • “De-Escalation” of DAT for Patients Undergoing PCI for Acute MI

  • ARNI in HFrEF post-AMI - PARADISE-MI | JW

  • ARNI vs Valsartan on NT-proBNP and Exercise Capacity in HFpEF

  • SGLT-2 Inhibitors and GLP-1–Receptor Agonists for CV RR in DM2

  • LUS–Guided ED Management of AHF (BLUSHED-AHF)

  • Triggers of Paroxysmal Atrial Fibrillation: The I-STOP-AFib

  • ICD Shocks with Subcutaneous vs. Transvenous ICD

  • Concomitant tricuspid repair in MR intervention

  • Valve Replacement for Severe Asymptomatic Aortic Stenosis?

  • Posterior left pericardiotomy for the prevention of AF after cardiac surgery

• Cirurgia

  • Are Antibiotics Required for Mild Acute Diverticulitis?

• COVID-19

  • Vacina Moderna aos 6 meses

  • Vacina Pfizer aos 6 meses

  • Inactivated SARS-CoV-2 vaccine (BBV152)

  • CVnCoV mRNA vaccine in ten countries in Europe and Latin America

  • ChAdOx1 or BNT162b2 plus seasonal influenza vaccines (ComFluCOV)

  • COVID-19 (NVX-CoV2373) co-administered with seasonal influenza vaccines

  • ChAdOx1 nCoV-19 against SARS-CoV-2 during the delta (B.1.617.2) variant

  • Aspirin in patients admitted to hospital with COVID-19 (RECOVERY)

  • Inhaled Ciclesonide for Outpatient Treatment of Symptomatic COVID-19

  • Sarilumab in moderate-to-severe COVID-19 (CORIMUNO-SARI-1)

  • Transmission during a large, live, indoor gathering (SPRING)

• Doente crítico

  • Intravenous or Intraosseous Calcium vs Saline on ROSC

• Endocrinologia

  • Once-weekly cagrilintide in people with overweight and obesity

  • Adjustable intragastric balloon for treatment of obesity

• Gastroenterologia

  • Bowel Preparation Before Colonoscopy Using Virtual Reality Videos

  • Does Peppermint Oil Improve Symptoms of Irritable Bowel Syndrome?

• Geral

  • Effectiveness and Ethics of Incentives for Research Participation

  • Individualized Preventive Care Recommendations on Patient Interests

  • CBT in Chronic Pain

  • High or Low-Dose IM Ketorolac for Musculoskeletal Pain? — JournalFeed

• Geriatria & Paliativos

  • Primary Palliative Care Intervention on Patients With Advanced Cancer

  • Geriatric assessment improves toxic effects of cancer treatment (GAP70+)

• Infecciologia, Microbiologia & Antibióticos

  • Dalbavancin - Greater Cost, Lower Success? — JournalFeed

  • Secondary Antibiotic Prophylaxis for Latent Rheumatic Heart Disease

  • Amoxicillin Dose and Duration in Children with CAP: Is Less Just as Good?

  • Three-dose vaccine to Plasmodium falciparum in Mali - phase 1 trial

• Nefrologia

  • Can Chlorthalidone Lower BP in Patients with Advanced Kidney Disease?

  • Daprodustat for the Treatment of Anemia in Patients Undergoing Dialysis

  • Daprodustat for the Treatment of Anemia in Patients Not Undergoing Dialysis

• Neurologia

  • tPA before Endovascular Treatment for Stroke MR CLEAN NO IV

  • Ticagrelor vs Clopidogrel in CYP2C19 Loss-of-Function in TIA/Stroke NEJM

• Oncologia

  • Pembrolizumab for Persistent, Recurrent, or Metastatic Cervical Cancer

  • Ivosidenib for Advanced Cholangiocarcinoma With IDH1 Mutation

• Ortopedia & MFR

  • Strong vs Mild Opioid for Subacute Pain After Fractures Managed Surgically | JWatch

  • Is Complete Rest Really the Best Treatment for Sports-Related Concussions?

  • Comparing Telehealth-Delivered Exercise and Weight Loss on Knee OA

• Pneumologia

  • Should Steroid Dosing in COPD Exacerbations Be Individualized?

• Psiquiatria

  • Prevention of Major Depression in Older Adults With Insomnia

Guidelines

• Doente crítico

  • New Surviving Sepsis Guidelines

• Gastroenterologia

  • Adult Acute and Acute-on-Chronic Liver Failure in the ICU

  • “Clinical Care Pathway” for Nonalcoholic Fatty Liver Disease

Revisão de Estudos Observacionais (com ou sem ECA’s)

• Cardiologia

  • ESC 0/1-Hour, 0/2-Hour, and 0/3-Hour Algorithms for Rapid Triage of AMI

• Cirurgia

  • Assessment of Intercostal Nerve Block Analgesia for Thoracic Surgery

• COVID-19

  • Effectiveness of public health measures in covid-19 and SARS-CoV-2

• Neurologia

  • Immunotherapeutic Management of NMdA Receptor Antibody Encephalitis

  • Transient Focal Neurological Events in Cerebral Amyloid Angiopathy

Prospectivos

• Cardiologia

  • Mental Stress–Induced Myocardial Ischemia and Cardiovascular Events

  • Acute Consumption of Alcohol and Discrete Atrial Fibrillation Events

  • The Real-World Calculation of the HEART Score - interrater realiability

  • Further Evidence to Support a Low-Sodium, High-Potassium Diet

  • Catheter Ablation of VT in Patients With Cardiac Sarcoidosis

  • Improving Efficiency of Automated Office Blood Pressure Measurements

  • Extracoronary Arterial Abnormalities in Coronary Artery Dissection

• COVID-19

  • Inactivated virus-based SARS-CoV-2 vaccine, BBV152, in India

  • Vacina Moderna - Vacinados há 6M vs. Vacinados recentemente

  • Status and the Detection of SARS-CoV-2 Infection in HCP

  • Humoral and cellular response to BNT162b2 in targeted immunosuppression

  • Ab in Solid Organ Transplant patients receiving 4 Doses of mRNA Vaccine

  • SARS-CoV-2 and Psychological Distress and Prescribing, Fatigue and Sleep

  • Mental Health of High School Students After Lifting of Remote Schooling

  • Fungal infections in mechanically ventilated: French multicentre MYCOVID

• Doente crítico

  • Prevalence of Midline Cervical Spine Tenderness without Traumatic Injury

• Gastroenterologia

  • No Associations Between Regular Use of PPI’s and mortality

• Geral

  • Intradermal Sterile Water for Back Pain? — JournalFeed

• Endocrinologia

  • Parathyroidectomy and risk fracture

• Hematologia

  • Risk for Recurrent VTE in Patients With Subsegmental PE wo/ AC

• Infecciologia, Microbiologia & Antibióticos

  • Overprescribing Antibiotics & Downstream Healthcare Utilization

• Neurologia

  • Retinal Nerve Fiber Layer Thickness and Depressive Symptoms Over Time

• Oncologia

  • Atezolizumab, Nivolumab, and Docetaxel in Previously Treated NSCLC

  • AI–Augmented for Histologic Classification of Colorectal Polyps

Retrospectivos

• Cardiologia

  • Effectiveness and Safety of ACE vs. ARB: A Multinational Cohort Study

  • Statin and Progression of Coronary Atherosclerotic Plaque Composition

  • TTR Amyloid Cardiomyopathy in Patients With HFpEF

  • Event-Free and OS With Dapagliflozin in HFrEF

  • HS Benefit with Empagliflozin in Heart Failure with pEF

  • Atrial Fibrillation Burden and Health-Related QoL After AF Ablation

  • Association of Sodium-Glucose Transport Protein 2 Inhibitor and Gout

  • Prevalence of Medications That May Raise BP Among Adults With HT

  • Economic Outcomes of Rehabilitation in Elderly With AHF (REHAB-HF)

• Doente crítico

  • Prehospital Treatment of Status Epilepticus in the United States

  • Pre-Charging the Defibrillator Before Rhythm Checks in Cardiac Arrest

  • Midline vs Peripherally Inserted Central Catheters for Short-term Indications

  • Time = Brain in Carbon Monoxide Poisoning — JournalFeed

  • How Many Medics Does It Take to Get ROSC? No Joke! — JournalFeed

• COVID-19

  • Prior SARS-CoV-2 Infection and Risk of Breakthrough Infection

  • Automated Text Messaging Service for Monitoring COVID-19 at Home

  • Self-reported COVID-19 Infection and SARS-CoV-2 Serology

  • SARS-CoV-2 Antibodies Among Children in Montreal, Canada

  • BNT162b2 vaccine and risk of SARS-CoV-2 infection: test negative study

  • Effectiveness of Ad26.COV2.S Adenoviral Vector Vaccine for COVID-19

  • Estimated Effectiveness of mRNA COVID-19 Vaccines Among Veterans

  • Breakthrough Infection in Vaccinated Patients with Multiple Myeloma

  • Vaccination and COVID-19 Hospitalization and Disease Severity

  • COVID-19 Vaccine and SARS-CoV-2 Infection and Mortality in a MIC

  • Odds of Positive Following Receipt of 3 vs 2 Doses of the BNT162b2 Vaccine

  • Incidence of CVST After Ad26.COV2.S Vaccination

  • CVST in SARS-CoV-2 VIIT

  • Myocardial Infarction, Stroke, and PE After BNT162b2 mRNA

  • Factors Associated With Risk of Postdischarge Thrombosis

  • Serum Ferritin Levels and Methylprednisolone Treatment

  • D-Dimer to Exclude Pulmonary Embolism Among Patients With COVID-19

  • Mortality Risk Among Patients With COVID-19 Prescribed SSRI

• Gastroenterologia

  • Liver Biopsy in Diagnosis and Management of High-grade ICI-Hepatitis

• Geral

  • Association Between Physician Part-time Clinical Work and Patient Outcomes

  • Smoking Relapse Among Who Switched From Cigarettes to Other Tobacco

  • Long-term use of PPIs is associated with an increased risk of type 2 diabetes

  • Primary Care, Telemedicine and In-Person Visits

  • Medication Harms Leading to Emergency Department Visits

• Hematologia

  • Neutralization of SARS-CoV-2 Variants in Transplant Recipients after 3 doses

• Infecciologia, Microbiologia & Antibióticos

  • GBS Following Recombinant Zoster Vaccine in Medicare Beneficiaries

• Nefrologia

  • Risk Score for Acute Kidney Injury After Percutaneous Coronary Intervention

• Neurologia

  • Noncontrast CT vs CT Perfusion or MRI Selection in LVO Stroke

  • Dimethyl Fumarate vs Fingolimod and Rituximab vs Natalizumab for MS

  • Deep Learning Model for Earlier Detection of Cognitive Decline

  • Does This Patient Have Cauda Equina? — JournalFeed

• Pneumologia

  • Pulmonary Rehabilitation After Hospitalization for COPD Exacerbations

• Psiquiatria

  • Social Media Use and Self-reported Symptoms of Depression in US Adults

• Oncologia

  • Uptake and Survival Following ICI Among Trial-Ineligible Patients

  • Clinical and Toxic Effects of Single-Agent ICI Among Geriatric

  • Patient preferences in communicating Life Expectancy in Prostate Cancer

  • Cost-effectiveness Studies for Oncology Drugs in the US 2015-2020

  • Cost-Effectiveness of Screening Mammography Beyond Age 75 Years

• Urologia

  • Changes in PSA after USPSTF modification on Prostate Cancer Screening

CASO CLÍNICO

• Cardio - Not All Electrocardiographic ST-Elevations Are Acute Coronary Occlusions

• Infecto - A Possible Sterilizing Cure of HIV-1 Infection

• Onco - Dermatomyositis With CUPHN

REVISÃO NÃO-SISTEMÁTICA

• Vaccine-induced immune thrombotic thrombocytopenia

OUTROS

• MBE

  • Diagnostic Excellence Through the Lens of Patient-Centeredness

  • Confidence Intervals in Interpreting Nonstatistically Significant Results

  • Discordant and inappropriate discordant recommendations in guidelines

  • Should COVID-19 vaccination be mandatory?