Março 23 - Inventário do mês
Atualizado: 11 de abr.
Neste inventário mensal deixo uma lista com todos os artigos com que me fui deparando. Como nem todos são muito relevantes ou modificadores de prática mas apenas pessoalmente interessantes ou importantes para alertar nuances, resolvi começar a usar uma forma de os sinalizar e diferenciar. Em última instância, isto é tudo muito subjectivo e relacionado com o meu interesse particular de médico generalista e internista português de base hospitalar.
Glossário*:
✔✔✔ --> Muito relevante e interessante
✔ --> Relevante e interessante
(sem símbolo) --> Interessante mas pouco relevante
(sem símbolo) --> Pouco relevante e interessante
✗ --> Não relevante e pouco interessante (mas importante por contrariar hipóteses, práticas, ...)
*classificação pessoal, nem todos concordarão
TABELA DE CONTÉUDOS:
REVISÕES SISTEMÁTICAS de ECAs
Cardiovascular
✔ CRT Improves Outcomes in Patients w/ Intraventricular Conduction Delay But Not RBBB | CIRCULATION
Doente crítico/urgente
✔✔✔ Effect of Corticosteroids on Mortality and Clinical Cure in Community-Acquired Pneumonia | CHEST
✔✔✔ Epinephrine in OHCA: NMA and Subgroup Analyses of Shockable and Nonshockable Rhythms | Chest
Infecciologia, Microbiologia & Antimicrobianos
✔✔✔ SARS-CoV-2 vaccines efficacy and dose–response relationship with antibodies | Lancet Microbe
✔ Effects of remdesivir in patients hospitalised with COVID-19 | Lancet Respiratory Medicine
The association between PCSK9 inhibitor use and sepsis | AJM ✗
Meta-investigação & MBE
✔ Meta-Analysis of Candidate Surrogate End Points in Advanced Prostate Cancer | NEJM Evidence
Oncologia
1st-line Systemic Treatment for Metastatic Castration-Sensitive Prostate Cancer | JAMA Oncology - Spin
Organ-specific immune checkpoint inhibitor treatment in lung cancer | BMJ Open
Urologia
✔ Antimuscarinics plus alpha-blockers in BPH with urinary storage symptom of BPH | Urology
ENSAIOS CONTROLADOS E ALEATORIZADOS
Cardiovascular
✔✔✔ Rule-out of non-STE ACS by a single Troponin test - ARTICA | EHJ
✔✔✔ Routine Invasive vs Conservative Strategy in Older Frailty Adults w/ NSTEMI-MOSCA-FRAIL | JAMA IM
✔ Phase 3 Trial of Sotatercept for Treatment of Pulmonary Arterial Hypertension - STELLAR | NEJM
✔ Non-physician community health-care provider-led vs standard BP intervention - CRHCP | Lancet
✔ Rate-Adaptive Atrial Pacing for Heart Failure With Preserved Ejection Fraction - RAPID-AF | JAMA
Treat-to-Target or High-Intensity Statin in Patients w/ CAD - LODESTAR | JAMA
Acute Effects of Coffee Consumption on Health among Ambulatory Adults - CRAVE | NEJM
Ambulatory Decision Support Tools to Improve Heart Failure Care - BETTER CARE_HF | JACC
Immediate vs staged complete revascularisation in ACS and multivessel CD - BIOVASC | Lancet
Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients - CLEAR | NEJM
Transcatheter Repair for Patients with Tricuspid Regurgitation - TRILUMINATE | NEJM
Endovascular Ultrasound Renal Denervation to Treat Hypertension | JAMA
Doente crítico/urgente
✔✔✔ Hydrocortisone in Severe Community-Acquired Pneumonia - CAPE COD | NEJM
✔ Lateral Decubitus or Upright Positioning Optimal for LP Success in a Teaching Hospital? | JEM
✔ Low vs standard calorie and protein in ventilated shocked patients, NUTRIREA-3 | Lancet RM - Controlo não standard
Endocrinologia
Gastroenterologia & Hepatologia
One-food vs six-food elimination diet for the treatment of eosinophilic oesophagitis | Lancet G&H - pq não 0-food?
Etrasimod as induction and maintenance therapy for ulcerative colitis - ELEVATE UC 52 + 12 | Lancet - sem comparador
Over-the-Scope Clips vs Standard Endoscopy as the Initial Treatment in Nonvariceal UGIB | AIM - sem melhoria clínica
Geral, Geriatria & Paliativos
✔ Genicular nerve block for pain management in knee OA | AR
Hematologia
Garadacimab (FXIIa inhibitor) for hereditary angioedema prevention - VANGUARD | Lancet - Sem comparador activo
✗ Ferric carboxymaltose vs oral iron for preop IDAnaemia in colorectal cancer - FIT | Lancet G&H - Spin
Imuno-mediadas
✔ Temporary Methotrexate Discontinuation in RA for 1W vs 2W on Influenza Vaccination | A&R
✔ Treatment with rituximab in polymyalgia rheumatica - BRIDGE-AMR | Lancet Rheumatology
Baricitinib for SLE: a double-blind RC phase 3 trial - SLE-BRAVE-I | Lancet - Sem comparador activo
Baricitinib for SLE: a double-blind RC phase 3 trial - SLE-BRAVE-II | Lancet - Sem comparador activo
Lebrikizumab for Moderate-to-Severe Atopic Dermatitis - ADvocate 1 & ADvocate 2 | NEJM - Sem comparador activo
Vedolizumab for the Treatment of Chronic Pouchitis | NEJM - Sem comparador activo
Infecciologia, Microbiologia & Antimicrobianos
✔ Multifaceted antibiotic stewardship for suspected UTI in frail older adults - ImpresU | The BMJ
✔ Electronic nudges to increase influenza vaccination uptake in Denmark | Lancet - Giro...mas clinicamente relevante?
IV doxycycline vs azithromycin vs both in Severe Scrub Typhus (O. tstutsugamushi) - INTEREST | NEJM - Spin
✗ Proph, High-dose proph, and therapeutic AC in Hypoxemic COVID-19 Pneumonia - ANTICOVID | JAMA IM - Spin
Neurologia
✔✔✔ High-Intensity Interval Walking Training for Stroke Patients | JAMA Neurology
Oncologia
Pneumologia
✔ Effects of Opt-out vs Opt-in Tobacco Treatment on Engagement, Cessation, and Costs | JAMA IM
Digital measurement of medical adherence and lung function in uncontrolled asthma - INCA Sun | Lancet RM - clinicamente relevante?
Psiquiatria
Antidepressant Augmentation versus Switch in Treatment-Resistant Geriatric Depression | NEJM - Melhor tratamento disponível?
✗ Integrating Alcohol-Related Prevention and Treatment Into Primary Care | JAMA IM - Sobrediagnóstico?
Técnicas, POCUS, Exames & Outros
✔ Hyperfractionationed RT for locally advanced recurrent nasopharyngeal carcinoma | Lancet
NORMAS DE ORIENTAÇÃO CLÍNICAS - GUIDELINES
Cardiovascular
✔ High sensivity Troponin for Evaluation and Diagnosis of Acute Chest Pain - Consensus | Circulation
Doente crítico/urgente
Surgical Management and Mechanical Circulatory Support in High-Risk PE | Circulation
Gastroenterologia & Hepatologia
✔ Management of Acute Lower Gastrointestinal Bleeding: An Updated ACG Guideline | AJG
ESTUDOS OBSERVACIONAIS
REVISÕES SISTEMÁTICAS COM ESTUDOS OBSERVACIONAIS (com ou sem ECA)
Cardiovascular
Ionising radiation and cardiovascular disease: systematic review and meta-analysis | BMJ - clinicamente relevante?
Dermatologia
✔ Prevalence of misdiagnosis of cellulitis: A systematic review and meta-analysis | JHM
Doente crítico/urgente
Geral, Geriatria & Paliativos
Potentiality of algorithms and AI adoption to improve medication management in primary care | BMJ
Infecciologia, Microbiologia & Antimicrobianos
✔✔✔ Past SARS-CoV-2 infection protection against re-infection | Lancet
✔ Prevalence of misdiagnosis of cellulitis: A systematic review and meta-analysis | JHM
Meta-investigação & MBE
✔ Challenges of Shared Decision-making in Low-risk Differentiated Thyroid Cancer | JAMA OHN
Psiquiatria
Peripheral cytokines and inflammatory proteins in acute/chronic stages of schizophrenia | Lancet Psy
SUB-ANÁLISES DE ECAs
Cardiovascular
✔✔✔ Time course of death after ACS treated with dual antiplatelet therapy for one year | AJM
✔✔✔ REVIVED-BCIS2 subanalysis | ACC 2023 meeting
✔ 3y Outcomes After TAVI or SAVR in Low-Risk Patients with Aortic Stenosis | JACC
Cirurgia, Ortopedia & MFR
Infecciologia, Microbiologia & Antimicrobianos
Meta-investigação & MBE
NLP of EHRs to Measure GoC Discussions as a Clinical Trial Outcome | JAMA Network Open
Oncologia
COORTE E CASO-CONTROLO
Cardiovascular
✔✔✔ Effect of IV antihypertensives in severe HT in hospitalized patients | Hypertension
✔✔✔ Differential effect of anticoagulation according to cognitive function and frailty in AF | JAGS
✔✔✔ Benefits and harms of OAC for AF in nursing home residents with advanced dementia | JAGS
✔ Incidence of Cardiac Arrest During Sports Among Women in the European Union | JACC
✔ Hyperacute T Wave in the Early Diagnosis of Acute Myocardial Infarction | AEM
✗ Early peripheral vascular interventions for claudication, late interventions and progression to chronic ischemia | JVS - bom exemplo do que não se deve fazer
Cirurgia, Ortopedia & MFR
✔ Low serum creatinine and associated outcomes after nonemergent inpatient surgery | AS
✔ Perioperative assessment of frailty and 1-year mortality | JAMA Surgery
Surgeon-Anesthesiologist Dyad and Postoperative Outcomes | JAMA Surgery
Doente crítico/urgente
✔ Prevalence of pulmonary embolism among patients with recent onset of dyspnea on exertion | JTH
✔ ETCO2 at ED Triage vs Triage Vital Signs in Predicting In-Hospital Mortality and ICU admission | AEM
✔ Continued vs Paused Chest Compressions During Cardiac Arrest in the ED | Resuscitation
Endocrinologia
✔✔✔Osmotic Demyelination Syndrome in Patients Hospitalized with Hyponatremia | NEJM Evidence
✔ Serum sodium, cognition and incident dementia in the general population | AaA
✔ Long-Term Changes in the Size of Pituitary Microadenomas | AIM
Geral, Geriatria & Paliativos
✔ ✔ ✔ FDA Mandate Limiting Acetaminophen/Opioid Combination Opioid Products and outcomes | JAMA
✔ Tell-a provider about tele: Reducing overuse of telemetry across 10 hospitals in a safety net system
Agressive EOL Care among Metastatic Cancer | JAMA NO
Imuno-mediadas
Infecciologia, Microbiologia & Antimicrobianos
✔✔✔ Real-world Application of Oral Therapy for Infective Endocarditis | Clinical Infectious Diseases
✔✔✔ Positive impact of PET/CT on mortality in SA bacteremia explained by immortal time bias | CID
✔✔✔ Association of PPI with Risk of Acquiring Drug-Resistant Enterobacterales | JAMA Network Open
✔ Optimal duration for hospitalized patients with complicated UTIs and associated bacteremia | CID
✔ Penicillin susceptibility among MSSA osteoarticular infections in children | AAC
Meta-investigação & MBE
Trends of Randomized Clinical Trials Citing Prior Systematic Reviews, 2007-2021 | JAMA Network Open
Neurologia
✔✔✔ Population-based evaluation of total protein in cerebrospinal fluid | MCP
✔ Conversion Between the Montreal Cognitive Assessment and the Mini-Mental State Examination | AGS
Placental growth factor as a sensitive biomarker for vascular cognitive impairment | A&D
Visual Creativity in Frontotemporal Dementia | JAMA Neurology
Serum NfLC at Disease Onset and Worsening after First Demyelinating MS | JAMA Neurology
Seasonality of human sleep: Polysomnographic data of a neuropsychiatric sleep clinic | Frontiers
Oncologia
✔ Fifteen-year outcomes after monitoring, surgery, or radiotherapy for prostate cancer | NEJM
ERBB2-Low Breast Cancer Among Patients in the National Cancer Database | JAMA Oncology
Pneumologia
Stepping up IC dose in Asthma | JACIP
Técnicas, POCUS, Exames & Outros
CASOS E SÉRIES
Cardiovascular
Platypnea-Orthodeoxia Syndrome: A Rare Cause of Hypoxia | AIM
Cirurgia, Ortopedia & MFR
Left-Sided Acute Appendicitis With Situs Inversus Totalis | AIM
Dermatologia
Erythema Gyratum Repens Secondary to Pulmonary Tuberculosis | AIM
Fibrofolliculomas: The Clue to the Diagnosis of Birt-Hogg-Dubé Syndrome | AMP
Doenças Raras
Endocrinologia
A Patient With Diabetes and Spontaneous Blistering of the Right Lower Extremity | JAMA
Hematologia
Swollen gums in a young adult | BMJ
Imuno-mediadas
Infecciologia, Microbiologia & Antimicrobianos
An Uncommon Cause of Severe Polyradiculopathy | AIM
A Man With Asymptomatic Ulcerated White Plaques on the Soft Palate | JAMA
Neurologia
Pro-Ictal State in Human Temporal Lobe Epilepsy | NEJM Evidence
A Young Man With Recurrent Syncope | AIM
Pneumologia
Lungs of a Chronic Smoker: The Case of Heroin-Induced Emphysema in a 35-Year-Old Man | AIM
Erasmus Syndrome: An Underrecognized Entity | AMP
INQUÉRITOS
Geral, Geriatria & Paliativos
✔✔✔ Assessment of Patient Education Delivered at Time of Hospital Discharge | JAMA Internal Medicine
Meta-investigação & MBE
✔✔✔ Political endorsement by Nature and trust in scientific expertise during COVID-19 | Nature
Nefrologia
OPINIÃO
REVISÃO NÃO-SISTEMÁTICA / NARRATIVA
Cardiovascular
Gastroenterologia & Hepatologia
Diagnosis and management of autoimmune hepatitis | The BMJ
Imuno-mediadas
Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management | BMJ
Neurologia
✔ Endovascular treatment for basilar artery occlusion: a meta-analysis | BMJ SVN
Técnicas, POCUS, Exames & Outros
Indications, Clinical Impact, and Complications of Critical Care TEE: A Scoping Review | SAGE
PERSPECTIVA
Gastroenterologia & Hepatologia
✔✔✔ Interpreting the results from the first RCT of colonoscopy: does it save lives? | BMJ-EBM
Geral, Geriatria & Paliativos
✔✔✔ Diagnostic Stewardship to Prevent Diagnostic Error | JAMA
Infecciologia, Microbiologia & Antimicrobianos
✔✔✔ Can the Future of ID Escape the Inertial Dogma? Shorter Is Better and Oral Is the New IV | OFID
As Superbugs Flourish, Bacteriophage Therapy Recaptures Researchers Interest | JAM
H5N1: Governments should invest in vaccines for all flu strains, says WHO chief scientist | BMJ
Meta-investigação & MBE
✔ Omission of Critical Information From Clinical Trial Reports—What to Do | JAMA Oncology
Digitally enabled decentralised research: opportunities to improve the efficiency | BMJ EBM
Oncologia
✔✔✔ Dear Oncology Fellows: We Must All Stand Up For Patients | Sensible Medicine
Psiquiatria
✔ NICE recommends online therapies to treat depression and anxiety in adults | BMJ
Técnicas, POCUS, Exames & Outros
✔✔✔ FOAMed
Cardiovascular
Cirurgia, Ortopedia & MFR
#336 ASA in TKA and THA Patients: Back to the future for VTE prophylaxis? - Tools for practice
Doente crítico/urgente
Role of Point-of-Care Ultrasound in Emergency Airway Management Outside the Operating Room | Analgesia
Geral, Geriatria & Paliativos
Episode 64 – Stopping the Shakes – The Curious Clinicians
Episode 63 – Getting Swol – The Curious Clinicians
Meta-investigação & MBE
Do not fear AI, pony humans | St. Emlyn's
Nefrologia
Vacillation in Atrial Fibrillation on Hemodialysis Continues — NephJC
#384 Updates in Chronic Kidney Disease with Dr. Joel Topf - The Curbsiders
Técnicas, POCUS, Exames & Outros
SGEM#398: ANOTHER AB GETS BUSED – POCUS IN THE ED FOR BILIARY DISEASE | The SGEM
ARA - Aumento de Risco Absoluto | ECA - Ensaio clínico aleatorizado | ITA - Intention-to-treat Analysis | MA - Meta-análise | MBE - Medicina baseada na evidência | NIT - Non-inferiority trial | NNH - Number needed to harm | NNT - Number needed to treat | PPA - Per protocol analysis | RRA - Redução do Risco Absoluto | RS - Revisão Sistemática