Verão 2022 (Julho, Agosto e Setembro)

JULHO

Meta-Revisão

• Contextual effects in general medicine: meta-epidemiological study | BMJ EBM

RS de ECA

• Cardiovascular

  • Blood pressure-lowering treatment for cardiovascular diseases in T2DM | Lancet

• Cirurgia, Ortopedia & MFR

  • Placebo and Nonoperative Control Groups in Surgical Trials | JAMA Network Open

• COVID-19

  • Janus kinase inhibitors for the treatment of COVID-19 | Cochrane

• Doente crítico/urgente

  • Balanced solutions vs isotonic saline in diabetic ketoacidosis | Heart & Lung: TJCAC

• Endocrinologia

  • DPP-4 Inhibitors Confer Some Risk for Gallbladder and Biliary Disease | BMJ

• Geral, Geriatria & Paliativos

  • Benzodiazepines or Antihistamines for Patients With Acute Vertigo | JAMA

• Hematologia

  • Anticoagulants for thrombosis prophylaxis in acutely ill patients | The BMJ

• Infecciologia, Microbiologia & Antimicrobianos

  • Effects of therapies for Ebola virus disease | Lancet Microbe

• Meta-investigação & MBE

  • Data Sharing by Pharmaceuticals for Anticancer Medicines by FDA | JAMA Onco

• Nefrologia

  • N-acetylcysteine and Acute Kidney Injury After Contrast Administration | JAMA NO

• Neurologia

  • Acute- and long-term pharmacological treatment for insomnia in adults | The Lancet

• Pneumologia

  • Home oxygen for moderate hypoxaemia in COPD | Lancet Respiratory Medicine

• Psiquiatria

  • Combining vs Monotherapy Antidepressant for Acute Depression | JAMA Psychiatry

ECA

• Cardiovascular

  • Midazolam vs morphine in acute cardiogenic pulmonary oedema | EJHF

  • Emergency vs Delayed Coronary Angiogram in NSTEMI OHCA - EMERGE | JAMA C

  • Early Empagliflozin on Diuresis and Kidney Function in ADHF EMPAG-HF | Circulation

  • Moderate-intensity statin / ezetimibe vs high-intensity statin (RACING) | Lancet

  • Omecamtiv Mecarbil on Exercise Capacity in CHF w/ reduced EF | JAMA

• Cirurgia, Ortopedia & MFR

  • Corticosteroid vs Placebo Injection (+exercise) for Achilles Tendinopathy | JAMA NO

  • Sacral Neuromodulation for Neurogenic Lower Urinary Tract Dysfunction | NEJM

  • Gastric Bypass vs Sleeve Gastrectomy on Diabetes Remission | Diabetes Care

• COVID-19

  • High-Dose Dexamethasone and Oxygen Strategies in ICU patients | JAMA IM

• Doente crítico/urgente

  • 4% Albumin vs Ringer Acetate on Major AE in Cardiac Surgery w/ bypass | JAMA

  • Intranasal TXA+PE/LC vs PE/LC alone in Atraumatic Anterior Epistaxis | AEM

  • High- vs Low-Dose TxA on need for RBC and AE in Cardiac Surgery - OPTIMAL | JAMA

  • Plasma vs NaCl for Trauma-Coagulopathy in Hemorrhagic Shock Risk - PREHO-PLYO | JAMA NO

• Endocrinologia

  • Aflibercept Monotherapy or Bevacizumab First for Diabetic Macular Edema | NEJM

• Gastroenterologia & Hepatologia

  • Procalcitonin-based algorithm in acute pancreatitis (PROCAP) | Lancet G&H

  • Liraglutide vs colesevelam for the treatment of bile acid diarrhoea | Lancet G&H

• Geral, Geriatria & Paliativos

  • Electroacupuncture on Insomnia in Patients With Depression | JAMA Network Open

• Imuno-mediado

  • Remote CBA and PEP for chronic fatigue in rheumatic diseases - LIFT | Lancet Rheum

  • Low dose, add-on prednisolone in RA aged 65+ - GLORIA | Annals of the Rheum Dis

• Infecciologia, Microbiologia & Antimicrobianos

  • Antibiotic prophylaxis vs no in transperineal prostate biopsies (NORAPP) | Lancet

  • Computerised decision support for hospital antibiotic use (COMPASS) | Lancet

  • 2d vs 7d levofloxacin in acute COPD exacerbation | TARD

  • Oteseconazole in Recurrent Vulvovaginal Candidiasis | NEJM Evidence

• Nefrologia

  • Rosuvastatin and Hematuria and Proteinuria | American Society of Nephrology

• Neurologia

  • Tenecteplase vs alteplase for AIS in Canada - AcT (ol, mc, NIT) | Lancet Neuro

  • EVT alone vs EVT plus tPA - SWIFT-DIRECT, non-inferiority RCT | Lancet Neurology

  • EVT alone vs EVT plus tPA - DIRECT-SAFE, non-inferiority RCT | Lancet Neurology

• Oncologia

  • Overall Survival w/ Brentuximab Vedotin in III or IV Hodgkin’s Lymphoma | NEJM

  • Pembrolizumab + Chemotherapy in Advanced Triple-Negative Breast Cancer | NEJM

  • Topical Hypericin Photodynamic Therapy - Early CTCL/Mycosis Fungoides|JAMA Onc

• Psiquiatria

  • Pharmacogenomic Testing for Drug-Gene Interactions in MDD - PRIME Care | JAMA

NORMAS DE ORIENTAÇÃO CLÍNICAS (GUIDELINES):

• Pneumologia

  • Therapy for Mild to Moderate Asthma - GINA | JAMA

---------------------------------------------------------- OBSERVACIONAIS --------------------------------------------------

RS COM ESTUDOS OBSERVACIONAIS (com ou sem ECA)

• COVID-19

  • Dexamethasone in hospitalised patients not on intensive respiratory support | ERJ

  • Update Alert 11: Epidemiology and Risk Factors for Infection in HCW | AIM

• Gastroenterologia & Hepatologia

  • Prevalence and incidence of NAFLD worldwide | Lancet G&H

• Geral, Geriatria & Paliativos

  • Cannabis-Based Products for Chronic Pain: A Systematic Review | AIM

• Imuno-mediado

  • Stopping Biologics for Rheumatologic Disease Before Surgery | JBSA

• Oncologia

  • Toxicity of ICI vs TKI for Advanced Hepatocellular Carcinoma | JAMA NO

PROSPECTIVOS

• Cardiovascular

  • Subanalysis of REDUCE-IT Biomarker Substudy | Circulation

  • Subanalysis of DECLARE-TIMI-48 regarding other GDT | JAMA Cardiology

• Cirurgia, Ortopedia & MFR

  • Physical Therapy vs Meniscectomy in Degenerative Meniscal Tears at 5y | JAMA NO

  • Antibiotic Therapy for Uncomplicated Appendicitis: More Data from CODA|JAMA NO

  • Laparoscopic vs Open Distal Gastrectomy - 5y of KLASS-02 | JAMA Surgery

• Gastroenterologia & Hepatologia

  • Hp Eradication on Cancer Prevention - 26.5y Follow-up of RCT | Gastroenterology

• Geral, Geriatria & Paliativos

  • “Weekend Warrior” vs Other Physical Activity Patterns | JAMA IM

  • ‘It was like being hit with a brick’: diagnosis of eye disease in PC and SC | BMJ Open

• Imuno-mediado

  • Rituximab in systemic sclerosis: open-label extension of DESIRES | Lancet Rheuma

• Meta-investigação & MBE

  • Physicians’ Probability Estimates of a Medical Outcome | JAMA

• Pneumologia

  • E-Cigarettes Among Cannabis-Naive Adolescents and Cannabis Use | JAMA NetOpen

RETROSPECTIVOS

• Cardiovascular

  • Etiologies of Type 2 MI - Secondary Analysis of High-STEACS | JAMA Network Open

  • HFpEF Among Patients With Unexplained Dyspnea | JAMA Cardiology

  • Switching Warfarin to a DOAC based in TTR Recommendations | JAMA Net Open

  • Sitting Time, Mortality and Cardiovascular Events | JAMA Cardiology

  • Atrial Fibrillation After Noncardiac Surgery vs nonoperative AF | AIM

  • Risk and Timing of Noncardiac Surgery After TAVI | JAMA Network Open

• Endocrinologia

  • Prolonged Use of PPIs and Type 2 Diabetes | The Journal of Clinical Endocr & Metabo

  • Kidney Stone After Parathyroidectomy vs Nonoperative - Primary HiperPTH|JCEM

• Geral, Geriatria & Paliativos

  • Choosing wisely in adult hospital: co-creation of new recommendations | JGIM

• Hematologia

  • Risks of Steroid Use in Patients with Sickle Cell Disease | Blood

• Imuno-mediado

  • Rituximab for Induction and Maintenance in >75y w/ ANCA Vasculitis | JAMA NetO

• Infecciologia, Microbiologia & Antimicrobianos

  • Demographic and clinical characteristics of human monkeypox in the UK | Lancet ID

  • Outbreak of sexually transmitted XDR Shigella sonnei in the UK, 2021–22 | Lancet M

  • Antibiotic Prescribing during the AHRQSP for Improving Antibiotic Use | JAMA NO

  • Adding Molecular Analysis to the Diagnostic Toolbox for Infective Endocarditis | CID

  • Monkeypox Virus Infection in Humans across 16 Countries April-June 2022 | NEJM

• Nefrologia

  • Quantifying Individual-Level Inaccuracy in GFRe: A Cross-Sectional Study | AIM

  • Arterial and Venous Thromboembolism and Bleeding in Nephrotic Syndrome | AJM

• Neurologia

  • Ischemic Stroke - CT Alone vs CT+MRI | JAMA Network Open

  • Pattern of Recovery Following Intracerebral Hemorrhage | JAMA Neurology

• Oncologia

  • Second brain tumour post RT for pituitary adenoma/craniopharyngioma |LancetD&E

  • Artificial Intelligence Model for Small Bowel Capsule Endoscopy | JAMA NetOpen

  • Second Primary Cancer after RT vs Surgery on Prostate Cancer Treatment | JAMA NO

• Pneumologia

  • Patterns in e-Cigarette Use Among Adults in the US, 2017-2020 | JAMA NetOpen

CASO CLÍNICO / IMAGEM CLÍNICA

• Coração e vasos - Human Response to a Porcine Heart Transplant - NEJM

• Infecções - Radical treatment for blastomycosis | Lancet M

• Sistema nervoso central e periférico - Nonketotic Hyperglycemic Hemichorea

REVISÃO NÃO-SISTEMÁTICA / NARRATIVA

• Meta-investigação & MBE

  • A Framework for the Development of Living Practice Guidelines in Health Care | AIM

ARTIGO DE OPINIÃO

• Geral, Geriatria & Paliativos

  • Welcoming of the New Interns to the Profession: May the Force Be With You | AIM

• Imuno-mediado

  • NICE approves romosozumab for postmenopausal osteoporosis | Lancet Rheuma

• Meta-investigação & MBE

  • Patient-Reported Outcomes Measures - JAMA Network Open

  • Path for medical associations to sponsor trustworthy guidelines: is it feasible? - PMC

  • Evidence-based medicine has already adapted and is very much alive | BMJ-EBM

  • Adapt or die: how the pandemic made the shift from EBM to EBM+ | BMJ-EBM

FOAMed

• Doente crítico/urgente

  • TFP #318 -Tranexamic Acid - Golden in the golden hours of trauma?

  • Tiny Tips: PETMAC as a mnemonic for the 6 deadly causes of chest pain - CanadiEM

• Endocrinologia

  • Goliath the Giant | Core IM Podcast

• Hematologia

  • 5 Pearls On Sickle Cell | Core IM Podcast

• Imuno-mediado

• Infecciologia, Microbiologia & Antimicrobianos

  • Drug Fever and Antibiotic-Associated Neurotoxicity: Gray Matters Segment | Core IM

• Meta-investigação & MBE

  • Non-Inferiority Trial | Core IM Podcast

  • Non-Inferiority Trial: Part 2 | Core IM Podcast

  • Intention to Treat | Core IM Podcast

• Pneumologia

  • 5 Pearls on COPD | Core IM Podcast

AGOSTO

RS de ECA

• Cardiovascular

  • DAT with Aspirin and Ticagrelor and Vein Graft Failure After CABG | JAMA

  • Anticoagulants for thrombosis prophylaxis in acutely ill hospitalized patients | BMJ

  • Salt substitutes on clinical outcomes: a systematic review and meta-analysis | Heart

  • Angiotensin receptor blockers and β blockers in Marfan syndrome | Lancet

  • Statins on muscle symptoms: an IPD-MA of large-scale double-blind RCTs | Lancet

• Cirurgia, Ortopedia & MFR

  • Different preoperative skin antiseptics on surgical site infections | Lancet Microbe

• Meta-investigação & MBE

  • Quality of HC interventions tested in Cochrane Reviews | J Clinical Epidemiology

• Oncologia

  • ICIs and Patient-Reported Outcomes / QoL | JAMA Network Open

• Psiquiatria

  • Response to acute monotherapy for major depressive disorder | The BMJ

ECA

• Cardiovascular

  • Walking Exercise in Lower Extremity Peripheral Artery Disease - The LITE | JAHA

  • Patiromer for hyperkalemia in HFrEF - DIAMOND trial | European Heart Journal

  • Standard vs Self-measurement of BP w/ a Smartphone Application | JAMA IM

  • Alerting Clinicians to 1-Y Mortality in Hospitalized HF - REVEAL-HF | JAMA Cardiology

ESC 2022

• Five-Year Outcomes of the Danish Cardiovascular Screening (DANCAVAS) Trial | NEJM

• Polypill Strategy in Secondary Cardiovascular Prevention | NEJM

• Fractional Flow Reserve vs Intravascular Ultrasonography in PCI - FLAVOUR | NEJM

• PCI for Ischemic Left Ventricular Dysfunction - REVIVED-BCIS2 | NEJM

• Routine Functional Testing or Standard Care in High-Risk Patients after PCI | NEJM

• Acetazolamide in ADHF with Volume Overload - ADVOR | NEJM

• Dapagliflozin in HFrEF - DELIVER | NEJM

• Empagliflozin in acute myocardial infarction: the EMMY trial | EHJ

• Rivaroxaban in Rheumatic Heart Disease–Associated Atrial Fibrillation | NEJM

• Cirurgia, Ortopedia & MFR

  • Graded Sensorimotor Retraining on Pain Intensity in Chronic Low Back Pain|JAMANO

  • Sentinel Lymph Node Biopsy vs Complete Dissection in Melanoma | JAMA Surgery

  • Removal of Small, Asymptomatic Kidney Stones and Incidence of Relapse | NEJM

  • Non-sterile vs sterile gloves, dressings and drapes for traumatic wounds | EMJ

• COVID-19

  • Metformin, Ivermectin, and Fluvoxamine for Covid-19 | NEJM Evidence

  • Sabizabulin for High-Risk, Hospitalized Adults with Covid-19 | NEJM Evidence

  • Hyperbaric oxygen in symptoms and function of post-COVID | Scientific Reports

• Doente crítico/urgente

  • Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM

  • Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest | NEJM

• Endocrinologia

  • Early Time-Restricted Eating for Weight and Fat Loss | JAMA Internal Medicine

  • Commercial vs Do-It-Yourself in Weight Management | JAMA Network Open

  • Tirzepatide + antihyperglycaemic PO in T2D in Japan - SURPASS J-combo | LancetD&E

  • Tirzepatide vs dulaglutide (+ ADO) in T2D in Japan - SURPASS J-mono | LancetD&E

  • Endoscopic sleeve gastroplasty vs Lifestyle for class 1 and 2 Obesity - MERIT | Lancet

• Gastroenterologia & Hepatologia

  • Diet or medication in primary care patients with IBS - DOMINO study | Gut

  • Group CBT w/ Interoceptive Exposure for Drug-Refractory IBS | AJG

• Geral, Geriatria & Paliativos

  • Amitriptyline, pregabalin, and duloxetine for diabetic NP - OPTION-DM | Lancet

  • Patient-Centered Pain Care Using AI and Mobile Health Tools | JAMA Internal Med

  • Direct-to-Consumer Advertising of Prescription Drugs | JAMA Health Forum

  • Remote vs In-home Physician Visits for Hospital-Level Care at Home | JAMA NetOpen

  • Intervention for reducing sitting time and improving health in office workers | BMJ

• Hematologia

  • Luspatercept for non-transfusion-dep β-thalassaemia-BEYOND | Lancet Haematology

• Imuno-mediado

  • Olokizumab vs Placebo or Adalimumab in Rheumatoid Arthritis - CREDO2 | NEJM

• Infecciologia, Microbiologia & Antimicrobianos

  • Bedaquiline–Pretomanid–Linezolid for Resistant Tuberculosis | NEJM

• Neurologia

  • Stenting vs Medical Therapy in Symptomatic Intracranial Stenosis - CASSIS | JAMA

  • IV Tirofiban vs Placebo Before EVT in Functionality in LVO Stroke - RESCUE-BT | JAMA

  • Remote Ischemic Conditioning in moderate AIS - The RICAMIS | JAMA

  • IV Ublituximab vs Oral Teriflunomide in Relapsing MS - ULTIMATE I and II | NEJM

• Oncologia

  • CT & x-ray vs X-ray for the follow-up of completely resected NSCLC | Lancet Oncology

  • Etoposide vs Irinotecan (plus Cisplatin) for Advanced Digestive NE - Lancet Oncology

  • RT Alone vs RT with CT (Cisplatin) on Low-risk Nasopharyngeal Carcinoma | JAMA

• Pneumologia

  • Varenicline and Cytisine for Alcohol Reduction in HIV and Substance Use | JAMA NO

• Psiquiatria

  • Heavy-drinking Days after Psilocybin-Assisted PT vs Placebo in AUD | JAMAPsychiatry

NORMAS DE ORIENTAÇÃO CLÍNICAS (GUIDELINES):

• Cardiovascular

  • Healthy Diet and Physical Activity for CVD Prevention in Adults wo/ CVR | JAMA

• Gastroenterologia & Hepatologia

  • Treatment of Clostridioides difficile Infection - ACG 2021 | JAMA

---------------------------------------------------------- OBSERVACIONAIS --------------------------------------------------

RS COM ESTUDOS OBSERVACIONAIS (com ou sem ECA)

• Meta-investigação & MBE

  • Recurrence-free vs overall survival - studies of resected CR liver metastasis | Lancet

• Oncologia

  • Low-Dose Methotrexate Exposure and Melanoma | JAMA Oncology

PROSPECTIVOS

• Cardiovascular

  • 5-Y Outcomes of SURTAVI (TAVI vs SAVR in Intermediate-Risk) - JAMA Cardiology

  • Efficacy and Safety of an Extravascular Implantable Cardioverter–Defibrillator | NEJM

• COVID-19

  • SARS-CoV-2 infectiousness and correlation with symptoms | Lancet Respiratory

• Risk Factors for Acute Incident VTE in Ambulatory Patients | JAMA Internal Medicine

• Hematologia

  • Low-Dose Decitabine vs Low-Dose Azacitidine in Lower-Risk MDS | NEJM Evidence

• Oncologia

  • De-escalation of RT after primary QT in cT1–2N1 breast cancer | Lancet Oncology

  • 5Y-OS of FOLFIRINOX vs Gemcitabine for Pancreatic Ductal AC | JAMA Oncology

RETROSPECTIVOS

• Cardiovascular

  • Continuous cuffless monitoring of arterial BP | Nature Nanotechnology

  • Cardiorespiratory Fitness and Mortality Risk | JACC

  • Cardiorespiratory fitness, obesity and LA function in patients with AF | IJC H&V

  • Post Hoc Analysis of the LOOP Trial on Severe Stroke | JAMA

  • Statin, MACE and Limbs in ESKD and PAD Patients Receiving Dialysis | JAMA NetOpen

• Cirurgia, Ortopedia & MFR

  • Open, laparoscopic and robotic inguinal hernia repair in the VA system | Hernia 2022

  • Endovascular vs Surgical Revascularization for Critical Limb Ischemia | JAMANetOpen

• Endocrinologia

  • Calories Purchased After Calorie Labeling of Prepared Foods | JAMA IM

• Infecciologia, Microbiologia & Antimicrobianos

  • Ultra-Short-Course Antibiotics for Suspected Pneumonia w/ SatO>95% | CID

  • A risk model to identify Legionella among hospitalized CAP|Journal of HospMedicine

• Nefrologia

  • Higher-Dose Fluoroquinolone and Serious AEs in Advanced CKD | JAMA Net Open

• Neurologia

  • Functional Recovery after Thrombectomy in LVO and pre-mRS 3-4 | JAMA Net Open

• Oncologia

  • Subcutaneous Panniculitis-like T-Cell Lymphoma | JAMA Oncology

  • Pre- and Posttreatment Nf Light Chain in ICANeurotoxicitySyndrome | JAMA O

CASO CLÍNICO / IMAGEM CLÍNICA

• Coração e vasos - Peri-infarction Pericarditis - A fading complication of MI | AIM

REVISÃO NÃO-SISTEMÁTICA / NARRATIVA

• Imuno-mediado

  • Gout: diagnosis and management—summary of NICE guidance | The BMJ

• Neurologia

  • Acute vertigo: getting the diagnosis right | The BMJ

ARTIGO DE OPINIÃO

• Infecciologia, Microbiologia & Antimicrobianos

  • What All Physicians Need to Know About the Polio Resurgence in New York | JAMA

FOAMed

• COVID-19

  • Baricitinib for hospitalised COVID19 patients. St Emlyn's

• Doente crítico/urgente

  • Ep 172 Syncope Simplified with David Carr - EMC

• Endocrinologia

  • Hyponatremia Management Part 1: 5 Pearls Segment | Core IM Podcast

• Geral, Geriatria & Paliativos

  • Episode 54 – A Lincoln Theory – The Curious Clinicians

• Meta-investigação & MBE

  • Verification Bias | Core IM Podcast

SETEMBRO

RS de ECA

• Cardiovascular

  • Optimal Pharmacologic Treatment of HFmrEF and HFpEF | JAMA Network Open

• SGLT-2 inhibitors in patients with heart failure | Lancet

• Infecciologia, Microbiologia & Antimicrobianos

  • Genitourinary Menopause Symptoms After Vaginal Laser vs Estrogen | JAMA NetO

• Meta-investigação & MBE

  • Patient-Reported Outcomes in Trials of Palliative Radiotherapy | JAMA NetworkOpen

  • Quality of reporting of RCTs of AI in healthcare: a systematic review | BMJ Open

ECA

• Cirurgia, Ortopedia & MFR

  • Robotic vs laparoscopic surgery for middle & low rectal cancer - REAL | Lancet G&H

  • Laparoscopy vs Open Surgery for Low Rectal Cancer - LASRE | Lancet Oncology

  • TIVA on Pulmonary Complications in Microvascular Surgery H&N Cancer | JAMA OHN

• COVID-19

  • Anti-C5a antibody (vilobelimab) for MV COVID-19 (PANAMO) | Lancet

  • Booster regimen of Ad26.COV2.S vaccine against COVID-19 - ENSEMBLE2 | Lancet ID

  • Baricitinib in hospitalized COVID-19 (RECOVERY) | The Lancet

  • Negative consequences of failing to communicate uncertainties | BMJ Open

• Endocrinologia

  • Open-Source Automated Insulin Delivery in Type 1 Diabetes | NEJM

  • Glycemia Reduction in T2D — Glycemic Outcomes | NEJM

  • Glycemia Reduction in T2D — Microvascular and Cardiovascular Outcomes | NEJM

• Gastroenterologia & Hepatologia

  • ABX464 (obefazimod) for moderate-to-severe, active ulcerative colitis | Lancet G&H

  • Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis - ERICA | NEJM

  • CT colonography vs 3x FIT 2/2y for colorectal cancer screening -SAVE | Lancet G&H

  • Faecal microbiota transplantation for 1st/2nd C. diff infection - EarlyFMT|LancetG&H

• Geral, Geriatria & Paliativos

  • Dexamethasone on dyspnoea in patients with cancer - ABCD | Lancet Oncology

  • Real-time Prescription Benefit Recommendations on Out-of-Pocket Costs | JAMA IM

• Hematologia

  • Asundexian (FXI inhibitor) after non-cardioembolic AIStroke - PACIFIC-Stroke | Lancet

• Imuno-mediado

  • Anti-BDCA2 Antibody Litifilimab for Systemic Lupus Erythematosus | NEJM

  • Pirfenidone in Rheumatoid Arthritis-associated Interstitial Lung Disease | Lancet

  • Rituximab for New-Onset Generalized MG - RINOMAX | JAMA Neurology

• Infecciologia, Microbiologia & Antimicrobianos

  • Two-day versus seven-day course of levofloxacin in acute COPD exacerbation | TARD

  • Single vs Multiple Proph AB in Implant-Based Breast Reconstruction | JAMA NetOpen

• Meta-investigação & MBE

  • Negative consequences of failing to communicate uncertainties | BMJ Open

  • Acupuncture for Anxiety Among Parkinson Disease | JAMA Network Open

• Neurologia

  • Prehospital Nitroglicerin in presumed acute stroke (MR ASAP) | Lancet Neurology

• Oncologia

  • Nivolumab + ipilimumab in resected IV melanoma wo/ disease - IMMUNED | Lancet

• POCUS

  • US for Femoral Vascular Access in Cardiac Procedures - UNIVERSAL | JAMACardiology

• Pneumologia

  • Bronchodilators in Tobacco-use and Symptoms but Preserved Lung Function | NEJM

NORMAS DE ORIENTAÇÃO CLÍNICAS (GUIDELINES):

• Cirurgia

  • Preoperative Management of Medications for Rheumatologic and HIV - SPAQI | MCP

  • Preoperative Management of Medications for Neurologic Diseases - SPAQI | MCP

  • Preoperative Management of Medications for Psychiatric Diseases - SPAQI | MCP

  • Preoperative Management of Gastrointestinal&Pulmonary Medications - SPAQI|MCP

• Psiquiatria

  • Major Depressive Disorder - US VA/DoD Guideline - Synopsis | AIM

---------------------------------------------------------- OBSERVACIONAIS --------------------------------------------------

RS COM ESTUDOS OBSERVACIONAIS (com ou sem ECA)

• Cardiovascular

  • Patient-Reported Outcomes Measures in Cardiovascular Disease | AIM

• Meta-investigação & MBE

  • FDA Accelerated Approval Program for Nononcology Drugs ‘92 <-> 2018 | JAMA NO

PROSPECTIVOS

• Cardiovascular

  • Five-Year Follow-up of MOMENTUM 3 (fully magnated vs axial-flow LVAD) | JAMA

  • Early Death in Patients Undergoing percutaneous LAAOC | JACC

  • 3y FU after SYMPLICITY-HTN-3, Renal Artery Denervation for Resistant HT | Lancet

• Endocrinologia

  • Prevalence and Characteristics of Incidental Adrenal Tumors | AIM

• Geral, Geriatria & Paliativos

  • Nonpharmacologic Interventions and Sleep in Hospitalized Patients | JAMA NetOpen

• Infecciologia, Microbiologia & Antimicrobianos

  • Digital-Observed vs Standard-Observed Therapy in Tuberculosis |JAMANetworkOpen

• Oncologia

  • Prophylactic Eat and Exercise during RT for Oropharyngeal Cancer | JAMA OHN

• Pneumologia

RETROSPECTIVOS

• Cardiovascular

  • Endotrophin, a Collagen VI Formation–Derived Peptide, in HF | NEJM Evidence

• Endocrinologia

  • Adrenal surgery for bilateral primary aldosteronism | Lancet D&E

  • Weight Loss w/ Semaglutide for Overweight or Obesity | JAMA Network Open

• Gastroenterologia & Hepatologia

  • Changes in prevalence of Helicobacter pylori in Japan from 2008 to 2018 | BMJ Open

• Geral, Geriatria & Paliativos

  • Periop Gabapentin and In-Hospital AEs in Olderly After Major Surgery | JAMA IM

• Infecciologia, Microbiologia & Antimicrobianos

  • ESBL E. Coli in France - Risk Factors | JAMA Network Open

• Oncologia

  • Simultaneous vs Delayed Liver Metastasis Resection in CRC | JAMA Network Open

CASO CLÍNICO / IMAGEM CLÍNICA

• Coração e vasos

  • Paget-Schroetter Syndrome in Nonathletic Without Hypercoagulopathy | AIM

• ECG

  • Huge Diagnostic and Treatment Challenges—A Confusing Coexistence | JAMA IM

• Sistema Gastrointestinal

  • Bouveret Syndrome | AIM

  • Pancreatic-Pleural Fistula in a Patient With Recurrent Pancreatitis | AIM

• Músculo-esquelético

  • Acute Lower-Extremity Posterior Compartment Syndrome w/ Apixaban | AIM

• Olho

• Pele e partes moles

  • Pyoderma Gangrenosum in MDS Mimicking Necrotizing Fasciitis | AIM

  • Systemic AL Amyloidoisis presenting w/ Painful Penile Ulcers | AIM

• Sistema nervoso central e periférico

  • Ophthalmoplegia and Tumor Lysis Syndrome | AIM

REVISÃO NÃO-SISTEMÁTICA / NARRATIVA

• Gastroenterologia & Hepatologia

  • Updates on Clostridioides difficile Infection for Hospitalists | AIM

• Hematologia

  • Diagnosis and Treatment of Myelodysplastic Syndromes | JAMA Network Open

  • Deep Venous Thrombosis | AIM

ARTIGO DE OPINIÃO

• Cardiovascular

  • New Research from the ESC Congress 2022

• Geral, Geriatria & Paliativos

  • Perioperative Gabapentin Use in Older Adults | JAMA IM

• Meta-investigação & MBE

  • Avoiding Definitive Conclusions in MAs of Heterogeneous and Small RCTs | JAMA

FOAMed

• Imuno-mediado

  • Tratamento Intensivo da Gota | ISBE - NL 125

• POCUS

  • Cholecystitis - CORE IM