2021 - Dezembro
Atualizado: 10 de nov. de 2022

ECA - Ensaio clínico aleatorizado | MBE - Medicina baseada na evidência | RS - Revisão Sistemática
RS de ECA
Endocrinologia
Diets for weight management in adults with type 2 diabetes | Diabetologia
Pharmacotherapy for adults with overweight and obesity | The Lancet
Intermittent Fasting: Umbrella Review of MA of RCT | JAMA Network Open
Gastroenterologia
Biologics and small molecule drugs for moderate-to-severe UC, Lancet
MBE & Meta-investigação
Conventional vs network MA about antibiotic prophylaxis in cancer and HSCT
Spin in noninferiority RCTs w/ nonsignificant results in Oncology - JAMA NO
Neurologia
Ticagrelor vs Clopidogrel w/ Aspirin in Minor Ischemic Stroke and TIA
Oncologia
ECA
Cirurgia
Regional vs General Anesthesia on Postop Delirium in Elderly | JAMA NO
Periop Patient Education via Animated Videos in H&Neck Surgery | JAMA
COVID-19
Ad5-nCov (recombinant adenovirus vaccine) in 18 years and older | Lancet
Heterologous COVID-19 vaccination (Com-COV2 NIT) - The Lancet
Third dose (booster) following ChAdOx1 or BNT, Lancet | ISBE
Immunogenicity and safety of a third dose of CoronaVac - Lancet
Ab 4 wks after Heterologous booster in Kidney Transplant | JAMA IM
Early Remdesivir Progression Prevention to Severe Covid in Outpat | NEJM
Molnupiravir in Nonvaccinated Nonhospitalized Patients | NEJM
nAB for Hospitalized Patients According to Baseline Ag Levels | AIM
Two nAB, sotrovimab and BRII-196 plus BRII-198 (TICO) - The Lancet
Lenzilumab in hospitalised COVID-19 pneumonia (LIVE-AIR) | Editorial
Namilumab or infliximab vs SoC, proof of concept (CATALYST) - The Lancet
High-Flow Oxygen Therapy vs COT on IMV and Recovery in Severe COVID
Rivaroxaban for post-discharge thromboprophylaxis (MICHELLE) - Lancet
Doente crítico
Diagnostic Strategy in suspected PE - YEARS + D-Dimer vs D-dimer
Bougie vs Stylet on First Attempt Intubation - JAMA NO | First10EM
Multiorgan Focused Clinical US in Cardiopulmonary diagnosis | JAMA NO
Gastroenterologia
Hemostatic Powder in the treatment of Upper Nonvariceal Lesions - AIM
Intensive therapy vs standard for symptomatic intestinal CD - Lancet spin !
Geral
Algorithm to Stop Night Checks for Reducing Sleep Interruption | JAMA IM
Geriatria & Paliativos
Digital Health–Based Self-management Program in CD | JAMA NO
Hematologia
Imuno-mediado
TDM vs ST During Infliximab on Immune-Mediated Diseases | JAMA NO
Spesolimab (anti-IL36) for Generalized Pustular Psoriasis | NEJM
Infecciologia, Microbiologia & Antibióticos
Ivermectin and dihydroartemisinin–piperaquine against malaria | Lancet
Neurologia
DRI (COMT or MAO-B inhib) vs DA in uncontrolled PD w/ Levodopa | JAMA
Oncologia
PORT vs no-PORT in completely resected NSCLC N2 (Lung ART) - Lancet
Nivolumab vs sorafenib in advanced hepatocellular carcinoma - The Lancet
GnRHa in Premenopausal Women in Chemotherapy | JAMA Oncology
Telephone based management of AE during CT for early stage breast cancer
KdD vs Kd against relapsed or refractory multiple myeloma (CANDOR)
Second-Line Tisagenlecleucel or SC in Aggressive B-Cell Lymphoma - NEJM
Axicabtagene Ciloleucel as Second-Line Therapy for LBCL - NEJM
Ortopedia & MFR
Multifactorial falls prevention programme in older people - Cluster RCT
Pneumologia
Elexacaftor plus tezacaftor/ivacaftor vs tezacaftor/ivacaftor in CF | Lancet
Psiquiatria
GUIDELINES
COVID-19
Geriatria & Paliativos
Evaluation of guideline on Fall Prevention/Management for Older - JAMA NO
REVISÃO DE OBSERVACIONAIS (com ou sem ECA’s)
COVID-19
Neutralising antibody titres as predictors of protection against SARS-CoV-2
Doente Crítico
Safety and Efficiency of Diagnostic Strategies for Ruling Out PE | AIM
Endocrinologia
Oral octreotide vs injectable SS receptor ligands in acromegaly - The Lancet
MBE & Meta-investigação
Trustworthiness of Guidelines for COVID-19 treatment - JAMA NO
Industry involvement in rheumatology recommendations - Lancet Rheuma
Oncologia
Anticancer Drugs Approved by the FDA According to Their MoA - JAMA NO
PROSPECTIVOS
Cardiovascular
Statin Discontinuation and Cardiovascular Events Among Older People
Variability in Reassessment of LVEF After Myocardial Infarction
Mobile Health–Technology pathway on AF in Multimorbidity | JAMA Network
Cirurgia
3D-CAM for Identification of post-OP Delirium in Older | JAMA Network Open
COVID-19
T-cell and Ab after first BNT162b2 vaccine dose in previously infected
CoronaVac and seropositivity in autoimmune RD - Lancet Rheumatology
Hybrid immunity vs vaccine-induced immunity in rheumatic diseases
Viral characteristics between alpha and delta / vaccinated and unvaccinated
Ab Response and Breakthrough Infection in Patients w/ Dialysis | AIM
Ab Titers Before and After a Third Dose of BNT162b2 Vaccine in Older Adults
BNT162b2 mRNA booster in actively treated patients w/ cancer - Lancet
COVID-19 Vaccine Type and AEs Following Vaccination | JAMA Network
SARS-CoV-2 antigen-detecting rapid tests for the delta and other variants
Assessment of Preferences for Telehealth in Post–COVID-19 Health Care
Geriatria & Paliativos
Preferences for Novel Care Modalities in Chronic Illness | JAMA NO
Imagiologia
AI–Based Chest X-ray Model on Human Nodule Detection | JAMA NO
MBE & Meta-investigação
Factors for Systematic Evidence Assessments in Clinical Trials
Nefrologia
Timing of dialysis initiation to reduce mortality and cardiovascular events
Neurologia
Twenty-Year Change in Outcome of Ischemic and Hemorrhagic Strokes - report bias
Endovascular Therapy in Acute Basilar Artery Occlusion | JAMA NO
Oncologia
USPSTF2013 vs PLCOm2012 for lung cancer screening - The Lancet
Pneumologia
e-Cigarette Among Smokers without Planning to Quit intention | JAMA NO
RETROSPECTIVOS
Cardiovascular
Prescribing of Statins After Lower Extremity Revascularization
Inclusion of Smoking Data in ASCVD Risk Calculator - JAMA Cardiology
Empagliflozin and background therapies, EMPEROR-Reduced post-hoc
Dapagliflozin and DM2 prevention, DAPA-HF & DAPA-CKD post-hoc
Cirurgia
Factors Relevant to Patients in Pain Control After Surgery - JAMA Network
COVID-19
Severity of Delta vs Beta Variant in Qatar | JAMA Internal Medicine
Omicron in South Africa - admissions and vaccine effectiveness | NEJM
Outcomes in South Africa during Omicron Wave vs. Other Waves | JAMA NO
Moderna, Pfizer and Janssen effectiveness against delta with time
Natural Immunity against reinfection with Alpha and Beta Variants
Immunogenicity of Extended mRNA SARS-CoV-2 Vaccine Dosing Intervals
Effectiveness of mRNA Vaccine Against Infection in Older Male | JAMA NO
mRNA Vaccination Effectiveness Against Infection or Death in Elderly | AIM
BNT162b2 Booster and Mortality Due to Covid-19 in Israel | NEJM
BNT162b2 Booster in Long-term Care Facilities in Israel | NEJM
Protection of BNT162b2 Booster across Age Groups in Israel | NEJM
Third BNT162b2 Vaccination Neutralization of beta, delta and omicron | NEJM
Testing Among Residential College Students in Connecticut | JAMA NO
Invasive pneumococcal disease after three COVID-19 waves in England
Myocarditis after Pfizer Vaccine in a Large Healthcare Organization (Israel)
Doente crítico
Thiamine Supplementation in Patients w/ Critical ilness and AUD - AIM
Endocrinologia
Gastroenterologia
CCR incidence, mortality, tumour characteristics, and treatment after FIT
APCAb and Gastric Cancer Risk in non-Hp women | JAMA Oncology
Hematologia
Recurrent VTE and Bleeding With Apixaban vs Rivaroxaban - AIM
Imuno-mediado
Mortality (All-cause, CVD & Cancer) in Bullous Pemphigoid | JAMA NO
Infecciologia, Microbiologia & Antibióticos
MBE & Meta-investigação
Low-Value Services Identified in US Choosing Wisely Recommendations
Financial Associations of Editorials and Sponsors on CV Intervention Trials
ML Algorithms for Predicting Progression to Dementia | JAMA Network Open
Comparison of Routinely Collected Data vs Clinical Adjudication | JAMA NO
Nefrologia
Patient-Specific Kidney Transplant Function w/ Deep Learning | JAMA NO
Neurologia
Thrombectomy for a low ASPECTS in early and extended window - JAMA NO
Antiseizure Drug and Mortality for Poststroke Epilepsy - JAMA Neurology - Spin Bias
Systolic BP and Dementia Risk with Age (U-shaped curve) - JAMA IM
Oncologia
CE vs US Imaging in diagnosing LN Metastasis in H&N CSCC | JAMA
2nd Generation Antiandrogens and Depression | JAMA Network Open
Ortopedia & MFR
Steroid Injections for Hip Osteoarthritis — Not Necessarily Benign
Pneumologia
Cardiovascular Safety for Smoking Cessation Pharmacotherapies in Australia
Psiquiatria
CASO CLÍNICO
ECG
Brugada pattern vs. Brugada syndrome - Differential Diagnosis
R-on-T phenomen After Diarrhea and Syncope in the Emergency Department
An Unusual Cause of Complete AVB in a Patient With Pedal Swelling
Transient ST-Segment Elevation and QTc Interval Prolongation
Músculo-esquelético - Severe Polyarthralgia After Kidney Transplant
ANÁLISE ECONÓMICA / CUSTO-EFECTIVIDADE / CUSTO-UTILIDADE
Cardiovascular
Cost-effectiveness of Cardiac Telerehabilitation w/ Relapse Prevention - CAD
Oncologia
Spending on 10 Accelerated Approved Drugs Lacking Clinical Benefit
CE 2021 vs 2013 USPSTF on Lung Cancer Screening - JAMA Oncology
OUTROS
Cardiovascular
Should practice change to antiHT bedtime administration? - BMJ EBM
Consider a CT angiogram before angiogram in NSTEMI - BMJ EBM
Alcohol and atrial fibrillation: to or not to drink? - BMJ EBM
COVID-19
COVID-19 Vaccine Makers Plan for Annual Boosters, but It's Not Clear They'll Be Needed
Bureaucracy has created a mess for Novavax volunteers like me
Covid-19: Antibody boost after third dose varies greatly by COV-BOOST
Vaccine strategies must focus on severe disease and global equity - Lancet
Risk Heterogeneity and the Illusion of Waning Vaccine Efficacy | AIM
Doente crítico
Epinephrine in the treatment of out-of-hospital cardiac arrest - BMJ EBM
Gastroenterologia
No role for TXA in the treatment of acute GI bleeding - BMJ EBM
Small intestine-release peppermint oil is beneficial in IBS - BMJ EBM
Geral
Preventing readmissions through better medication continuity - BMJ EBM
Less is more (JAMA)
Reconsidering Reliance on Positive Urine Drug Screen Results
MBE & Meta-investigação
Optimising the process of conducting a scoping review - BMJ-EBM
Neurologia
Thrombolysis w/ tPA 3-4.5h after AIS: trial reanalysis - BMJ EBM
Ortopedia & MFR
Virtual Reality Device Is Authorized to Relieve Back Pain | JAMA Network
Oncologia
Early salvage vs adjuvant therapy following prostatectomy - BMJ EBM
Pneumologia
RSV Vaccines Could Prevent Tens of Thousands of Yearly Deaths | JAMA
POCUS
The Cardiac Arrest Sonographic Assessment (CASA) exam – POCUS in PEA
POCUS — Visually Satisfying Medicine or Evidence-Based Medicine?
FOAMed
Cardiovascular
#310 No Tension About Inpatient HT - Dr. Noble Maleque, The Curbsiders
COVID-19
The CCEDRRN COVID-19 Infection Score (CCIS) Infographic - CanadiEM
Doente crítico
JC: Can we use smaller pigtail drains in traumatic haemothorax? • St Emlyn's
What is the Role of Contrast in Abdominal CT in the ED? - CanadiEM
Geral
Best Evidence: VTE prophylaxis in medical patients: is it worth it? - TI
Infecciologia, Microbiologia & Antibióticos
Nefrologia
Neurologia
Optimal management strategies for primary headache in the ED - CanadiEM
Thrombolysis + Thrombectomy for LVO Acute Ischemic Stroke | REBEL EM