Dezembro 22 - Lista do mês
ARA - Aumento de Risco Absoluto | ECA - Ensaio clínico aleatorizado | ITA - Intention-to-treat Analysis | MA - Meta-análise | MBE - Medicina baseada na evidência | NNH - Number needed to harm | NNT - Number needed to treat | PPA - Per protocol analysis | RRA - Redução do Risco Absoluto | RS - Revisão Sistemática
META-REVISÃO
Meta-investigação e MBE
Spin within SR abstracts on antiplatelet therapies after acute coronary syndrome | BMJ Open
REVISÕES SISTEMÁTICAS de ECAs
COVID-19
Awake prone positioning in covid-19 related hypoxemic respiratory failure | The BMJ
Infecciologia, Microbiologia & Antimicrobianos
Meta-investigação & MBE
Neurologia
Vestibular suppressants for benign paroxysmal positional vertigo | AcEM
Ler: What’s the Best Treatment for Peripheral Vertigo?
Efficacy and Safety of IV Thrombolysis and Thrombectomy Among Wake-Up Stroke | AEM
Ler: Concise Review of Lytics and Endovascular Therapy for ‘Wake Up’ Stroke – JournalFeed
Oncologia
ALK inhibitors in ALK-rearranged non-small cell lung cancer w/ and wo/ brain metastases | BMJ Open
Erlotinib plus bevacizumab vs erlotinib in EGFR+ advanced non-small-cell lung cancer | BMJ Open
ICIs in Advanced Esophageal Squamous Cell Carcinoma w/ Low PD-L1 Subgroups | JAMA Oncology
ENSAIOS CONTROLADOS E ALEATORIZADOS
Cardiovascular
Pharmacist-Led Telehealth vs Clinic-Based Care for Uncontrolled High Blood Pressure | Hypertension
Cirurgia, Ortopedia & MFR
Motion control vs neutral walking footwear on pain in lateral tibiofemoral joint OA| BMJ Open
COVID-19
Favipiravir in patients hospitalised with COVID-19 - PIONEER trial | The Lancet Respiratory Medicine
Molnupiravir plus usual care vs usual care for early high-risk COVID-19 - PANORAMIC | Lancet
High dose steroids in hospitalised COVID19 w/ hypoxia wo/ ventilatory support - RECOVERY|medRxiv
COVID-19 Vaccine Messaging Platforms in EDs on Vaccine Acceptance and Uptake | JAMA IM
Long-term (180-Day) Outcomes in Critically Ill COVID-19 Patients - REMAP-CAP | JAMA
Anticoagulation Strategies in Non–Critically Ill Patients with Covid-19 | NEJM Evidence
Dermatologia
Anti-OX40 Rocatinlimab in moderate-to-severe atopic dermatitis | The Lancet
Gastroenterologia & Hepatologia
2nd-line levofloxacin-based vs bismuth-based quadruple therapy for Hp eradication | Lancet G&H
Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis | NEJM
Community-Based Physical Activity Program for Type 2 Diabetes | JAMA Network Open
Biopsychosocial or Postural Therapy on Acute and Subacute Spine Pain | JAMA
Imuno-mediadas
Bimekizumab in psoriatic arthritis, naive to biologic treatment - BE OPTIMAL | The Lancet
Bimekizumab in active psoriatic arthritis refractory to TNFα-inhibitors - BE COMPLETE | The Lancet
Infecciologia, Microbiologia & Antimicrobianos
Rezafungin vs caspofungin for treatment of candidaemia and invasive candidiasis - ReSTORE | Lancet
Colistin Monotherapy vs Combination Therapy for Carbapenem-Resistant Organisms |NEJM Evidence
Meta-investigação & MBE
Feedback on Clinical Reasoning Competence Among Medical Students | JAMA Network Open
Nefrologia
Intervention to Improve Decision Making for Older Patients With Advanced CKD (Stages 4-5) | AIM
Neurologia
Safety/efficacy of tenecteplase in wake-up stroke assessed by non-contrast CT, TWIST | Lancet Neuro
Oncologia
Immediate surgery vs NeoA (gemcitabine+capecitabine, FOLFIRINOX or chemoradio) - ESPAC5 |LG&H
NORMAS DE ORIENTAÇÃO CLÍNICAS - GUIDELINES
Infecciologia, Microbiologia & Antimicrobianos
Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults - IAS-USA | JAMA
Pneumologia
2023 GOLD Report - Global Initiative for Chronic Obstructive Lung Disease - GOLD (goldcopd.org)
ESTUDOS OBSERVACIONAIS
RS COM ESTUDOS OBSERVACIONAIS (com ou sem ECA)
Doente crítico/urgente
Diagnostic Errors in the Emergency Department: Systematic Review | Effective Health Care Program
Infecciologia, Microbiologia & Antimicrobianos
Pneumococcal urinary antigen tests for patients with ARF and suspected pneumonia | BMJ Open
Social norm feedback on antibiotic prescribing and behaviour change techniques - | Lancet ID
Human rabies despite post-exposure prophylaxis - The Lancet Infectious Diseases
Pregnancy outcomes after first-trimester artemisinin vs non-artemisinin antimalarials | Lancet
Prognostic factors for streptococcal toxic shock syndrome | BMJ Open
Meta-investigação & MBE
Guidelines for Reporting Outcomes in Trial Reports: The CONSORT-Outcomes 2022 Extension | JAMA
Neurologia
Blood-Based Biomarkers in Adults With Peripheral Neuropathies | JAMA Network Open
Head CT in Geriatric ED Patients with Delirium, Altered Mental Status, and Confusion | AEM
Hearing Aids and Cochlear Implants w/ Cognitive Decline and Dementia | JAMA Neurology
SUB-ANÁLISES DE ECAs
Oncologia
Tucatinib + Trastuzumab/Capecitabine for Refractory HER2 BreastCancer w/ BrainMetastases | JAMA
COORTE, CASO-CONTROLO & COORTE TRANSVERSAL
Cardiovascular
Soluble CD146 in intravascular and tissue congestion in acute dyspnoea - analysis of LEDA | BMJOpen
Critical reassessment of the individual patient meta-analysis on bypass grafts by Gaudino et al
Rapid Exclusion of AMI w/ single hs-TnT in the ED: A Multicenter US Evaluation | CIRCULATION
Seamens’ Sign: a novel electrocardiogram prediction tool for left ventricular hypertrophy | PeerJ
Cirurgia, Ortopedia & MFR
Surgeon-Delivered Nerve Block for Less Perioperative Pain & Opioid Use on Spine Surgery | JAMA NO
Oxygen administration during surgery and postoperative organ injury: ohort study | The BMJ
COVID-19
Diagnostic yield of screening for SARS-CoV-2 among patients admitted to hospital | BMJ Open
Post-COVID 12 Weeks after Omicron and Vaccination compared to Negative Controls | CID
Association of SARS-CoV-2 w/ Patient-Reported Well-being 3M After Symptomatic Illness | JAMA NO
Extent and nature of duplication in PROSPERO using COVID-19-related registrations | BMJ Open
Doente crítico/urgente
Inhaled Nitric Oxide vs Epoprostenol During Acute Respiratory Failure - CHEST
Haemodynamic effects of 10-min high inspired O2 concentration in the ED | BMJ Open
Comparison of YEARS and Adjust-Unlikely D-dimer Testing for Pulmonary Embolism in the ED | AEM
Implementation of the Modified Canadian C-Spine Rule by Paramedics | AEM
Geral, Geriatria & Paliativos
Association of 5α-Reductase Inhibitors w/ Dementia, Depression, and Suicide | JAMA Network Open
Infecciologia, Microbiologia & Antimicrobianos
Linezolid and Risk of Serotonin Syndrome in Patients Receiving Antidepressants | JAMA NetOpen
Meta-investigação & MBE
Diagnostic Reasoning and the Accuracy of Findings in the History and Physical Examination
Clinical Study Results Reported in medRxiv Preprints vs Peer-reviewed Journal | JAMA Network Open
Retracted papers originating from paper mills: cross sectional study | The BMJ
Neurologia
Delayed ICH after head injury among elderly patients on anticoagulation seen in the ED | CJEM
Repeat Posttraumatic Brain CT in Elderly w/ Minimal Head Trauma and Antithrombotic Use | AEM
Antiepileptic Drugs and Incident Parkinson Disease in the UK Biobank | JAMA Neurology
Endovascular Thrombectomy vs Medical Management Beyond 24 Hours | JAMA Neurology
Oncologia
Yield of Surveillance Imaging After Mastectomy in Prior Breast Cancer | JAMA Network Open
ANÁLISE ECONÓMICA
Cardiovascular
Compression Therapy w/ Early Endovenous Ablation in Venous Ulceration | JAMA Network Open
INQUÉRITOS / QUALITATIVOS
Geral, Geriatria & Paliativos
Experiences of palliative / geriatric non-operative management of hip fracture patients | BMJ Open
CASO CLÍNICO / IMAGEM CLÍNICA
Cardiovascular
A Case of Isolated Cardiac Sarcoidosis | Annals of Internal Medicine
“Trench Foot” on the Banks of Lake Geneva: A Severe Case of Nonfreezing Cold Injury | AIM
Dermatologia
Cachexia and Diffuse “Fish-Scale” Skin | Annals of Internal Medicine
Gastroenterologia & Hepatologia
Ruptured Hepatic Subcapsular Hematoma after Heparin for Submassive Pulmonary Embolism | AIM
Imuno-mediadas
Severe Cervicodynia in a Patient With Pustules on the Palms | JAMA Neurology
Infecciologia, Microbiologia & Antimicrobianos
A Case of Multiple Skin Lesions After LipodissolveTM Injection | Annals of Internal Medicine
Kaposi Sarcoma: A Forgotten Complication in Well-Controlled HIV | Annals of Internal Medicine
Nefrologia
Page Kidney From Ruptured Mycotic Pseudoaneurysm of Renal Artery | Annals of Internal Medicine
Neurologia
Recurrent Cryptogenic Stroke in a Young Woman: Congenital TTTP Unmasked | Annals of IM
OPINIÃO
REVISÃO NÃO-SISTEMÁTICA / NARRATIVA
Geral, Geriatria & Paliativos
Gabapentin Will Not Cure the Opioid Crisis | JAMA Internal Medicine
Infecciologia, Microbiologia & Antimicrobianos
When and How to Use MIC in Clinical Practice? | Antibiotics
Meta-investigação & MBE
Is a one-size-fits-all ‘12-month rule’ appropriate to the last search date in SR? | BMJ EBM
PERSPECTIVA
Cardiovascular
NEJM Journal Watch Cardiology Top Stories of 2022 (jwatch.org)
COVID-19
The Tragedy of COVID19 | Sensible Medicine
Hematologia
Persistent challenges with treating multiple myeloma early | Blood - ASH
Infecciologia, Microbiologia & Antimicrobianos
Chaos in the Diagnosis of Pneumocystis Pneumonia - HIV and ID Observations
Meta-investigação & MBE
The limits of shared decision making | BMJ Evidence-Based Medicine
Neurologia
The Scent of Flavor | Linda Bartoshuk | Inference (inference-review.com)
Oncologia
The Tragedy of Oncology | Sensible Medicine
FDA Struggle to Withdraw Makena: Problems With the Accelerated Approval Process | JAMA
Preapproval Promises to Voluntarily Withdraw FDA-Approved Drugs | JAMA
Accelerated Approval Pathway: What Gives? - Chadi Nabhan | Sensible Medicine
FOAMed
Doente crítico/urgente
EMCrit 337 – Procedural Deep Dive – Lumbar Puncture (LP) | EMCrit
Laceration evidence: absorbable sutures or not? - First10EM
How far should sutures be spaced? - First10EM
Laceration evidence part 7: Aftercare instructions - First10EM
EMCrit 339 - Decisions, Decisions, Decisions with Andrew Petrosoniak
What's the down time? St Emlyn's • St Emlyn's (stemlynsblog.org)
Massive transfusion protocol: what is it, why does it exist, and when should I call one? - CanadiEM
Gastroenterologia & Hepatologia
Episode 62 – Connected Bilirubin – The Curious Clinicians
Geral, Geriatria & Paliativos
Handout #373 Recap Extravaganza 2022 - Curbsiders
Hope: At the Bedside Segment | Core IM Podcast
Imuno-mediadas
Episode 61 – Of ticks, alpha-gal, and red meat allergies – The Curious Clinicians
Infecciologia, Microbiologia & Antimicrobianos
REBEL Core Cast 92.0 - Perichondritis - REBEL EM - Emergency Medicine Blog
Nefrologia
Keep Calm and Carry on Inhibiting the RAS — NephJC
Neurologia
PulmCrit Blogitorial - SIESTA syndrome: Sedation Induced EEG Suppression with Transient Agitation
The efficacy and safety of orexin antagonists for insomnia - #328 Tools for Practice
Pneumologia
Bronchodilators or inhaled steroids for post-infectious cough - #329 Tools for Practice