Janeiro 23 - Inventário do mês
ARA - Aumento de Risco Absoluto | ECA - Ensaio clínico aleatorizado | ITA - Intention-to-treat Analysis | MA - Meta-análise | MBE - Medicina baseada na evidência | NIT - Non-inferiority trial | NNH - Number needed to harm | NNT - Number needed to treat | PPA - Per protocol analysis | RRA - Redução do Risco Absoluto | RS - Revisão Sistemática
REVISÕES SISTEMÁTICAS de ECAs
Cirurgia, Ortopedia & MFR
Doente crítico/urgente
Effect of Mobilization at 6 Months after Critical Illness | NEJM Evidence
Geral, Geriatria & Paliativos
Tramadol for knee or hip osteoarthritis | AC&R
Meta-investigação & MBE
Risk of Bias in RCTs of Transcatheter and Surgical Aortic Valve Replacement | JAMA Network Open
ENSAIOS CONTROLADOS E ALEATORIZADOS
Cardiovascular
Torsemide vs Furosemide after Discharge on Mortality in Hospitalized HF - TRANSFORM-HF | JAMA
Pulmonary Vein w/ Posterior Left Atrial Wall Isolation in Persistent AF - CAPLA | JAMA
Cirurgia, Ortopedia & MFR
Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture | NEJM
2 days versus 5 days of postoperative antibiotics for complex appendicitis - APPIC | Lancet
COVID-19
Fluvoxamine vs Placebo on Recovery in Outpatient Mild to Moderate COVID-19 - ACTIV-6 | JAMA
Visual-Olfactory Training for Patients With COVID-19 Resultant Olfactory Loss | JAMA OH&NS
Doente crítico/urgente
Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension | NEJM
Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest | NEJM
Fiber-Optic Intubation Among Resident Physicians After Higher- vs Lower-Fidelity Task Training | AA
Remifentanil vs Neuromuscular Blockers during RSI Among Patients at Risk of Aspiration | JAMA
Gastroenterologia & Hepatologia
Withdrawal of infliximab vs immunosuppressant in Crohn on combination - SPARE | LancetG&H
Geral, Geriatria & Paliativos
ML–Triggered Nudges on Serious Illness Conversations and End-of-Life Outcomes | JAMA Oncology
Infecciologia, Microbiologia & Antimicrobianos
Probiotic for pathogen-specific Staphylococcus aureus decolonisation in Thailand | Lancet Microbe
Nefrologia
Targeted-release budesonide for primary immunoglobulin A nephropathy - NefIgArd - Kidney Int
ORL
Self-treatment of Recurrent Benign Paroxysmal Positional Vertigo | JAMA Neurology
Técnicas, POCUS, Exames & Outros
MRI–Guided vs CT–Guided Stereotactic Body Radiotherapy for Prostate Cancer | JAMA Oncology
US in an impalpable tissue larynx model during a simulated front-of-neck access scenario | CEJM
Simulation-Based Training on Transesophageal Echocardiography - SIMULATOR | JAMA Cardiology
NORMAS DE ORIENTAÇÃO CLÍNICAS - GUIDELINES
Endocrinologia
Pharmacologic Treatment of Osteoporosis / Osteopenia - Living Clinical Guideline - ACP | AIM
Endocrine Society Hypercalcemia of Malignancy Guidelines | JAMA Oncology
Infecciologia, Microbiologia & Antimicrobianos
WHO fungal priority pathogens list to guide research, development and public health action
Nefrologia
Diabetes Management in CKD: Synopsis of the KDIGO 2022 Clinical Practice Guideline Update | AIM
ESTUDOS OBSERVACIONAIS
RS COM ESTUDOS OBSERVACIONAIS (com ou sem ECA)
Doente crítico/urgente
Safety Outcomes of Direct Discharge Home From ICUs | Critical Care Medicine
Endocrinologia
Treatments to Prevent Fractures in People With Low Bone Mass or Primary Osteoporosis | AIM
Infecciologia, Microbiologia & Antimicrobianos
Synovial Fluid and Serum Neutrophil-to-Lymphocyte Ratio for Native Septic Arthritis in Adults | BJSA
Acute Bacterial Infectious Conjunctivitis? | Rational Clinical Examination Systematic Review - JAMA
SUB-ANÁLISES DE ECAs
Cardiovascular
Mavacamten on Cardiopulmonary Exercise Testing - EXPLORER-HCM, Prespecified | JAMA Cardiology
Restoring mortality data in the FOURIER CVOT of evolocumab in patients with CVD | BMJ Open
Frailty and Multidomain Physical Rehabilitation in Elderly with Acute HF - REHAB | JAMA Cardiology
Doente crítico/urgente
Calcium in OHCA-PEA w/ Hyperkalemia-like or Ischemia-like EKG characteristics - COCA|Resuscitation
COORTE, CASO-CONTROLO & COORTE TRANSVERSAL
Cardiovascular
High-dose nitroglycerin infusion in sympathetic crashing acute pulmonary edema | AJEM
High sensitivity troponin – Six hours is the magic number | AJEM
Cirurgia, Ortopedia & MFR
Hemicolectomy vs appendectomy for appendiceal neuroendocrine tumours 1–2 cm in size | LancetO
Many Surgical Patients Might Not Need Pharmacologic VTE Prophylaxis | Annals of surgery
Doente crítico/urgente
Effectiveness of Amiodarone and Lidocaine for In-Hospital Cardiac Arrest (IHCA) treatment | Chest
Alcohol Withdrawal – Should We Reach For Phenobarbital? | AmJRCCM
Endocrinologia
SGLT2i vs DPP4i Inhibitor and Obstructive Airway Disease and Exacerbation | JAMA Network Open
Home Waking Salivary Cortisone to Screen for Adrenal Insufficiency | NEJM Evidence
Geral, Geriatria & Paliativos
Postoperative Restrictive Opioidand changes in prescribing and Chronic Use | JAMA Oncology
Hematologia
EBV Viral Load Monitoring Strategy and the Risk for PTLD in Adult Liver Transplantation | AIM
Imuno-mediadas
Hydroxychloroquine Dose and Risk for Incident Retinopathy | AIM
Infecciologia, Microbiologia & Antimicrobianos
Regional Antibiotic Delivery for Implanted Cardiovascular Electronic Device Infections | JACC
When Should MRSA Coverage Be Considered in Empiric Antibiotic Therapy for CAP? | AAC
Neurologia
Endovascular Brain-Computer Interface for Severe Paralysis in 4 Patients - SWITCH | JAMA Neurology
IV Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of DOACs | JAMA Neurology
Atrial Fibrillation Assessment after Embolic Stroke of Undetermined Source | Annals of Neurology
Oncologia
Osteoradionecrosis of the Jaw Following Proton Radiation Therapy for Head&Neck Cancer|JAMAOHN
Técnicas, POCUS, Exames & Outros
POCUS compression of the carotid artery for pulse determination in CPR | Resuscitation
Sensitivity of modern multisliceCT for SAH after headache onset: a 10-year analysis | EMJ
INQUÉRITOS / QUALITATIVOS
Geral, Geriatria & Paliativos
Analysis of Unmet Information Needs Among Patients With Thyroid Cancer | JAMA OH&NS
Meta-investigação & MBE
Financial conflicts of interest among US authors of 2020 clinical practice guidelines | BMJ Open
ANÁLISE ECONÓMICA
Cardiovascular
Anticoagulant Therapy for Cancer-Associated Thrombosis - Cost-effectiveness Analysis | AIM
Cirurgia, Ortopedia & MFR
Novel Macrophage-Regulating Treatment for Wound Healing in Diabetic Foot Ulcers | JAMA NO
Cost-effectiveness of Laparoscopic vs Open Gastrectomy for Gastric Cancer | JAMA Surgery
Laparoscopia ligeiramente mais cara (com QALYs iguais), mas a diferença a 1-ano foi mínima.
CASO CLÍNICO / IMAGEM CLÍNICA
Cardiovascular
Bilateral Subclavian Artery Stenosis Presenting as Refractory Hypotension | AIM
Cirurgia, Ortopedia & MFR
Gigantic Unruptured Abdominal Aneurysm Successfully Treated w/ Endovascular Repair (EVAR) | AIM
Endocrinologia
Symptomatic Calcification in a Patient With Normophosphatemic Tumoral Calcinosis | AIM
Scurvy's Systemic Clinical Picture: A Multiorgan Presentation of a Conspicuous Disease | AIM
Gastroenterologia & Hepatologia
Case of Ibuprofen-Induced Liver Injury | AIM
Medical Management of Emphysematous Gastritis | AIM
Cholecystalgia: Atypical Presentation of Congestive HF in Alcohol-Induced Cardiomyopathy | AIM
Hematologia
A Tale of Two Hematological Malignancies: CML Followed by CLL in the Same Patient | AIM
Imuno-mediadas
Dermatomyositis Presenting as Pseudo-angioedema | AIM
Immune Checkpoint Inhibitor-Induced Polyarthritis: A Case Series | AIM
Renal Sarcoidosis Presenting as Fanconi Syndrome
Infecciologia, Microbiologia & Antimicrobianos
Atypical Presentation of PML with Newly Diagnosed HIV Infection | AIM
Neurologia
Floccillation: A Diagnostic Clue to Delirium | AIM
Oncologia
Puzzling Case of Rapidly Progressive Global CNS Deterioration From IVLCL(DLBC) | AIM
OPINIÃO
REVISÃO NÃO-SISTEMÁTICA / NARRATIVA
Infecciologia, Microbiologia & Antimicrobianos
Management of Latent Tuberculosis Infection | JAMA
Neurologia
Migraine | Annals of Internal Medicine
Management of chronic migraine | The BMJ
PERSPECTIVA
Infecciologia, Microbiologia & Antimicrobianos
On the Rise, Candida auris Outwits Treatments and Travels Incognito in Health Care Settings | JAMA
Twenty-Strain “Universal” mRNA Flu Vaccine Effective in Animal Studies | JAMA
Neurologia
Lecanemab Linked to Death in AD Patient With Stroke Given tPA - Medscape / NEJM
Oncologia
Updated Labeling for Capecitabine, a 25-Year-Old Cancer Drug | JAMA
FOAMed
Cardiovascular
Atrial Fibrillation: Gray Matters Segment | Core IM Podcast
SGEM#388: It Makes No Difference Now - CCB or BB for AF w/ RVR in HFrEF - The SGEM
Doente crítico/urgente
Adult CXR Cases 028 • LITFL • CMC Radiology
Endocrinologia
#377 Adrenal Incidentalomas with Dr. William Young - The Curbsiders
Geral, Geriatria & Paliativos
#331 - Top 5 Tools for Practice of 2022 - Tools for practice
Infecciologia, Microbiologia & Antimicrobianos
Five Things Pharmacists Should Know About Ventilator Associated Pneumonia (VAP) | IDS
Nefrologia
PulmCrit – Myth-busting the conditional nephrotoxicity of piperacillin-tazobactam
Neurologia
#375 Delirium in the Hospital featuring Dr. Esther Oh - The Curbsiders
#370 Parkinson’s Disease for Primary Care with Dr. Albert Hung - The Curbsiders