Fevereiro 23 - Inventário do mês
ARA - Aumento de Risco Absoluto | ECA - Ensaio clínico aleatorizado | ITA - Intention-to-treat Analysis | MA - Meta-análise | MBE - Medicina baseada na evidência | NIT - Non-inferiority trial | NNH - Number needed to harm | NNT - Number needed to treat | PPA - Per protocol analysis | RRA - Redução do Risco Absoluto | RS - Revisão Sistemática
META-REVISÃO
Geral, Geriatria & Paliativos
Efficacy, safety, and tolerability of antidepressants for pain in adults | The BMJ
REVISÕES SISTEMÁTICAS de ECAs
Cardiovascular
Influenza Vaccination as a Prevention Therapy for Stable CAD and ACS | The AJM
Cirurgia, Ortopedia & MFR
Comparative Efficacy and Safety of Surgical Approaches for Total Hip Arthroplasty | JAMA NetOpen
COVID-19
Physical interventions to interrupt or reduce the spread of respiratory viruses | Cochrane Library
Doente crítico/urgente
The Effect of Mobilization at 6 Months after Critical Illness — Meta-Analysis | NEJM Evidence
Endocrinologia
GLP1-receptor agonists and A1c: Good for the heart but less so for the eyes? | D&MS
Psiquiatria
Nonpharmacologic/Pharmacologic Treatments of Adult Patients w/ Major Depressive Disorder | AIM
ENSAIOS CONTROLADOS E ALEATORIZADOS
Cardiovascular
Rivaroxaban vs Enoxaparin on MACE and Bleeding Risk in pre-PCI ACS - H-REPLACE | JAMA NO
Personalized Accelerated Pacing in Preclinical and Overt HFpEF - myPACE | JAMA
Cirurgia, Ortopedia & MFR
Lobar or Sublobar Resection for Peripheral Stage IA Non–Small-Cell Lung Cancer | NEJM
High- Versus Low-Dose Exercise Therapy for Knee Osteoarthritis | AIM
Doente crítico/urgente
Continued enteral nutrition vs fasting before extubation in the intensive care unit | Lancet RM
Early mobilisation on long-term cognitive impairment in critical illness in the USA | Lancet RM
Endocrinologia
Empagliflozin vs placebo & Linagliptin vs placebo in young people w/ T2D - DINAMO | Lancet D&E
Once-weekly basal Insulin Fc in T2D previously treated with basal insulin | Lancet D&E
Gastroenterologia & Hepatologia
Colesevelam for the treatment of bile acid diarrhoea - SINBAD | Lancet G&H
Disposable Elevator Cap Duodenoscopes and Microbial Contamination on ERCP - ICECAP | JAMA IM
Geral, Geriatria & Paliativos
Deprescribing Medications Among Elderly after hospitalization - Shed.MEDS | JAMA IM
Phase 2 Trial of Difelikefalin in Notalgia Paresthetica | NEJM
Hematologia
Allogeneic Transplantation vs CT in Intermediate-Risk Acute Myeloid Leukemia - ETAL-1 | JAMA O
Secukinumab in moderate-to-severe hidradenitis suppurativa (SUNSHINE and SUNRISE) | Lancet
Infecciologia, Microbiologia & Antimicrobianos
Treatment Strategy for Rifampin-Susceptible Tuberculosis - TRUNCATE-TB | NEJM
Respiratory Syncytial Virus Prefusion F Protein Vaccine in Older Adults | NEJM
Efficacy and Safety of an Ad26.RSV.preF–RSV preF Protein Vaccine in Older Adults - CYPRESS | NEJM
Antimicrobial stewardship prospective audit & feedback in hospitalised COVID-19-COVASP| Lancet ID
Antibiotic Prescription Audit and Feedback on Antibiotic Prescribing in Primary Care | JAMA IM
Nefrologia
Mycophenolate Mofetil Among Patients With Progressive IgA Nephropathy | JAMA Network Open
Sodium bicarbonate for kidney transplant recipients with metabolic acidosis in Switzerland | Lancet
Neurologia
Tenecteplase versus alteplase in acute ischaemic cerebrovascular events - TRACE-2 | Lancet
Argatroban + tPA vs tPA on Neurologic Function in 4.5h onset Acute Ischemic Stroke - ARAIS | JAMA
Trial of Globus Pallidus Focused Ultrasound Ablation in Parkinson’s Disease | NEJM
Biosimilar Natalizumab (PB006) in Relapsing-Remitting Multiple Sclerosis | JAMA Neurology
Oncologia
Temporary treatment cessation vs continuation of 1st-line TKI in advanced RCC - STAR | Lancet Onco
Hyaluronic Acid Spacer for Hypofractionated Prostate Radiation Therapy | JAMA Oncology
Breast-Conserving Surgery with or without Irradiation in Early Breast Cancer | NEJM
Temozolomide alone vs T w/ Interferon Alfa in High-grade Gliomas | JAMA Network Open
Psiquiatria
Oral THC alone or plus cannabidiol on THC Pharmacokinetics/dynamics | JAMA Network Open
Oral vs long-acting antipsychotic treatment in early-phase schizophrenia - EULAST| Lancet Psy
Active vs sham electrostimulation in major depression in primary care (Alpha-Stim-D) | Lancet Psy
NORMAS DE ORIENTAÇÃO CLÍNICAS - GUIDELINES
Geral, Geriatria & Paliativos
Opioids in the Management of Chronic Pain: Synopsis of the 2022 Updated US VA and DoD | AIM
Opioids for Adults With Pain From Cancer or Cancer Treatment: ASCO Guideline | JCO
Imuno-mediadas
2022 ACR guideline for vaccinations in rheumatological and musculoskeletal diseases | ACR
Psiquiatria
Nonpharmacologic and Pharmacologic Treatments in Acute Major Depressive Disorder | AIM
ESTUDOS OBSERVACIONAIS
RS COM ESTUDOS OBSERVACIONAIS (com ou sem ECA)
COVID-19
Comparability of Control and Comparison Groups in Studies Assessing Long COVID | AJM
Long-term effectiveness of COVID-19 vaccines in adults | Lancet RM
Previous SARS-CoV-2 and hybrid immunity against the omicron variant and severe disease | Lancet ID
Infecciologia, Microbiologia & Antimicrobianos
Association Between Antimicrobial Stewardship Programs and Antibiotic Use Globally | JAMA NetO
Standard of care for viral haemorrhagic fevers (VHFs) | Lancet ID
HCV point-of-care vs lab-based RNA viral load on turnaround times and adhesion | Lancet G&H
Incidence of infection with MDR Gram-negative bacteria and VRE in carriers | Lancet M
Antimicrobial resistance in patients COVID-19: a systematic review and meta-analysis | Lancet G&H
Psiquiatria
Values and Preferences about Pharmacologic and Nonpharmacologic Treatments for DD | AIM
SUB-ANÁLISES DE ECAs
Cardiovascular
Bradyarrhythmias in Patients Screened for Atrial Fibrillation vs Usual Care - LOOP | JAMA Cardiology
Dietary salt replaced with potassium-enriched salt in the SSaSS | Hypertension AHA
Endocrinologia
Moderate and Vigorous Aerobic Exercise on Diabetes and Obesity: A 10-Year Follow-up | JAMA IM
Children of women w/ T2D w/ metformin vs placebo during pregnancy - MiTy Kids | Lancet D&E
Pneumologia
Long-term safety & efficacy of tezepelumab in severe uncontrolled asthma,DESTINATION| Lancet RM
COORTE, CASO-CONTROLO & COORTE TRANSVERSAL
Cardiovascular
Temporal trends in the incidence of malignancy in heart failure: a nationwide Danish study | EHJ
ICD System Shock Function, Mortality, and Cause of Death After Magnetic Resonance Imaging | AIM
Cirurgia, Ortopedia & MFR
Telemedicine postoperative care among patients Undergoing Bariatric Surgery | JAMA Network Open
Doente crítico/urgente
STANDING algorithm by interns and senior emergency physicians for causes of vertigo | AEM
Weaning from mechanical ventilation in ICU across 50 countries - WEAN SAFE | Lancet RM
Endocrinologia
SGLT2 Inhibitors vs DPP-4 Inhibitors in Patients With Type 2 Diabetes and Varying HbA1c | JAMA IM
Geral, Geriatria & Paliativos
No Opioid Strategy at Discharge After Major Urologic Cancer Surgery - NOPIOIDS | JAMA Surgery
July 2018 worldwide valsartan recall and shortage on global trends | BMJ Open
The Safety of Inpatient Health Care | NEJM
Hematologia
Gene Therapy with Etranacogene Dezaparvovec for Hemophilia B | NEJM
Infecciologia, Microbiologia & Antimicrobianos
Household Transmission of Influenza A Viruses in 2021-2022 | JAMA
Meta-investigação & MBE
US FDA Approval of Drugs Not Meeting Pivotal Trial Primary End Points, 2018-2021 | JAMA IM
Drug Characteristics and Manufacturer Spending on Direct-to-Consumer Advertising | JAMA
Nefrologia
Serum NTpBNP and cystatin C for AKI in critically ill adults in China | BMJ Open
Endovascular thrombectomy beyond 24 hours of last known well: The SELECT late study | JAMA
Serum Glial Fibrillary Acidic Protein Compared vs Neurofilament Light Chain for MS | JAMANeurology
Frontotemporal Lobar Degeneration in 9 European Countries - FRONTIERS | JAMA Neurology
Guillain-Barré Syndrome After COVID-19 Vaccination in the US | JAMA Network Open
Oncologia
Radiation and Procarbazine for Hodgkin Lymphoma and Colorectal Cancer | JAMA Oncology
Deep Learning to Differentiate Colon Carcinoma From Acute Diverticulitis in CT | JAMA NetworkOpen
INQUÉRITOS / QUALITATIVOS
Meta-investigação & MBE
Trials Using Medical Writer Support in High-Impact Oncology Journals | JAMA Network Open
Patient-Reported Outcome Measures in Oncology Drugs Approved by the EMA | JAMA Net Open
ANÁLISE ECONÓMICA
Doente crítico/urgente
Chest Pain Management using Prehospital PoC Troponin and Paramedic Risk Assessment | JAMA IM
Psiquiatria
Cost-Effectiveness of First- / Second-Step Treatment Strategies for Major Depressive Disorder | AIM
CASO CLÍNICO / IMAGEM CLÍNICA
Cardiovascular
Unmasked by Fever: Diagnosing Brugada Syndrome After Ventricular Fibrillation Arrest | AIM
An Uncommon Cause of Acute Chest Pain | JAMA Internal Medicine
Endocrinologia
Apathetic Thyrotoxicosis Presenting With New-Onset Pulmonary Hypertension | AIM
Hematologia
Imuno-mediadas
ROSAH syndrome: childhood-onset arthritis, hand deformities, uveitis, and splenomegaly | Lancet R
Pseudo-Pseudo Meigs Syndrome as the Initial Presentation of Systemic Lupus Erythematosus | AIM
Infecciologia, Microbiologia & Antimicrobianos
Janeway Lesions as a Manifestation of Aortic Graft Abscess | AIM
Bivalvular Infective Endocarditis and Mural Vegetation Caused by Bartonella quintana | AIM
Man With Asymptomatic Ulcerated White Plaques on the Soft Palate | JAMA
Neurologia
MRI Features of GABA-A Receptor Antibody-Mediated Encephalitis | JAMA Neurology
OPINIÃO
REVISÃO NÃO-SISTEMÁTICA / NARRATIVA
Meta-investigação & MBE
Using Risk of Bias 2 to assess results from RCTs: guidance from Cochrane | BMJ EBM
Neurologia
Diagnosis of myelin oligodendrocyte glycoprotein antibody-associated disease | Lancet Neurology
Raciocínio clínico
Five strategies for clinicians to advance diagnostic excellence | The BMJ
PERSPECTIVA
Cardiovascular
Dapagliflozin Gets Expanded Heart Failure Indication in Europe | Medscape
NICE blocks wider use of Jardiance, Forxiga in heart failure | pharmaphorum
COVID-19
Hospital masking should be optional | Sensible Medicine
Geral, Geriatria & Paliativos
The Universal Panacea: Chicken Soup | The AMJ
Friday Reflection 14: Committing and Avoiding Medical Errors | Sensible Medicine
Hematologia
The Complete Blood Count: Increasing Its Precision and Impact | AIM
Infecciologia, Microbiologia & Antimicrobianos
Cholera is back but the world is looking away | The BMJ
The Importance of Shifting Sepsis Quality Measures From Processes to Outcomes | JAMA
Meta-investigação & MBE
Platform trials: the future of medical research? | Lancet RM
AI Bot ChatGPT Passes US Medical Licensing Exams Without Cramming – Unlike Students
Chess Lessons: Human Intelligence and Imitation Learning to Support Clinical Decisions | AIM
Nefrologia
Breaking the Link Between Enrollment in Hospice and Discontinuation of Dialysis | JAMA
Neurologia
Thrombolysis Not Necessary in Mild Nondisabling Stroke: ARAMIS | Medscape
FOAMed
Cardiovascular
Amiodarone vs Digoxin for Acute Rate Control of Atrial Fibrillation in the ED - REBEL EM
Tools for Practice - #332A Jab for Your CAD
Cirurgia, Ortopedia & MFR
REBEL Core Cast 94.0 - SBO - REBEL EM - Emergency Medicine Blog
COVID-19
VIZIR RCT – Zinc For COVID-19? | JF
Is zinc the cure for COVID? | First10EM
Doente crítico/urgente
Point-Counterpoint | IV Haloperidol Is Safe For Emergency Department Use | JF
Point-Counterpoint | IV Haloperidol Should Be Avoided In The Emergency Department | JF
We should stop using the Canadian CT head rule - First10EM
EMCrit 342 - More Cardiac Arrest Mastery with PO Berve - Pre-Tidal CO2
Gastroenterologia & Hepatologia
#380 Hemochromatosis with Elliot Tapper - The Curbsiders
Meta-investigação & MBE
Clinical decision rules are ruining medicine - First10EM
ORL
#379 Hearing Loss, Tinnitus, and Meniere's Disease - The Curbsiders