Abril de 2023 - Inventário do mês

TABELA DE CONTÉUDOS:

1. META-REVISÃO

2. REVISÕES SISTEMÁTICAS DE ECAs

3. ECAs

4. NORMAS DE ORIENTAÇÃO CLÍNICA

5. OBSERVACIONAIS

   1. Revisões Sistemáticas | Sub-análises de ECAs | Coortes e casos-controlo

   2. Séries e casos

   3. Inquéritos | Análises económicas

6. OPINIÃO

   1. Revisões narrativas | Perspectiva | FOAMed

Glossário:

✔✔✔ --> Muito relevante e interessante

✔ --> Relevante e interessante

(sem símbolo) --> Interessante mas pouco relevante

(sem símbolo) --> Pouco relevante e interessante

✗ --> Não relevante e pouco interessante (mas importante por contrariar hipóteses, práticas, ...)

classificação pessoal, nem todos concordarão

META-REVISÃO

Meta-investigação & MBE

✔✔✔ Wide Confidence Intervals in Meta-Analytic Estimates: ‘Absence of Evidence’ or ‘Evidence of Absence’? | SSRN

REVISÕES SISTEMÁTICAS de ECAs

tabela de conteúdos ↟

Cardiovascular

✔✔✔ IV Mg As An Adjunct To Standard Of Care For Atrial Fibrillation w/ Rapid Ventricular Response | AEM

✔ Comparison of seven popular structured dietary programmes, mortality and MACE in patients w/ CVR | BMJ

Doente crítico/urgente

✔ Therapeutic effects of vasopressin on cardiac arrest: a systematic review and meta-analysis | BMJ Open

Meta-investigação & MBE

✔ Completeness and Spin of medRxiv Preprint and Associated Published Abstracts of COVID-19 RCTs | JAMA

✔ Sharing of IPD by Trialists of Randomized Clinical Trials of Pharmacological Treatments for COVID-19 | JAMA

Neurologia

✔✔✔ Does melatonin administration reduce the incidence of postoperative delirium in adults? | BMJ Open

✔ Adverse Events of Cannabidiol Use in Patients With Epilepsy | JAMA Network Open

ENSAIOS CONTROLADOS E ALEATORIZADOS

tabela de conteúdos ↟

Cardiovascular

Heterogeneity in Blood Pressure Response to 4 Antihypertensive Drugs | JAMA

Effect of a Coaching Intervention to Improve Cardiologist Communication | JAMA Internal Medicine

Cirurgia, Ortopedia & MFR

Decompressive Craniectomy vs Craniotomy for Acute Subdural Hematoma - RESCUE-ASDH | NEJM

Doente crítico/urgente

✔✔✔ McGrath Mac videolaryngoscope vs conventional laryngoscopy | Anaesthesia

✔ Early adjunctive methylene blue in patients with septic shock: a randomized controlled trial | Critical care

Gastroenterologia & Hepatologia

✔ VE303 (Defined Bacterial Consortium) for Prevention of Clostridioides difficile Infection - CONSORTIUM | JAMA

Geral, Geriatria & Paliativos

Family Conferences to Facilitate Deprescribing in Older Outpatients w/ Frailty and Polypharmacy, COFRAIL| JAMA NO

Effectiveness of an over-the-counter self-fitting hearing aid compared w/ an audiologist-fitted hearing aid | JAMA OHN

Hematologia

Efficacy and safety of fitusiran prophylaxis in haemophilia A or haemophilia B with inhibitors - ATLAS-INH | Lancet

Infecciologia, Microbiologia & Antimicrobianos

✔ Higher dose steroids inpatient COVID-19 who are hypoxic but not requiring ventilatory support - RECOVERY | Lancet

Efficacy and Safety of a Bivalent RSV Prefusion F Vaccine in Older Adults - RENOIR | NEJM

Oral Fluvoxamine With Inhaled Budesonide for Treatment of Early-Onset COVID-19 - TOGETHER | AIM

Neurologia

✔ Trial of Endovascular Thrombectomy for Large Ischemic Strokes - SELECT2 | NEJM

✔ Trial of Endovascular Therapy for Acute Ischemic Stroke with Large Infarct - ANGEL-ASPECT | NEJM

Endovascular vs no endovascular treatment for ischemic stroke after 6–24h - MR CLEAN-LATE | Lancet

Pneumologia

Effect of Intrapleural Fibrinolytic Therapy vs Surgery for Complicated Pleural Infections | JAMA Network Open

Psiquiatria

Effectiveness of Conditioned Open-label Placebo With Methadone in Treatment of Opioid Use Disorder | JAMA

Técnicas, POCUS, Exames, Apoio Digital & Outros

✔ Management of Rheumatoid Arthritis With a Digital Health Application | JAMA

NORMAS DE ORIENTAÇÃO CLÍNICAS - GUIDELINES

tabela de conteúdos ↟

Cardiovascular

✔ Supervised Exercise Training for HFpEF: American Heart Association and American College of Cardiology | JACC

Cirurgia, Ortopedia & MFR

Management of Thoracic Aortic Dissection | JAMA

ESTUDOS OBSERVACIONAIS

REVISÕES SISTEMÁTICAS COM ESTUDOS OBSERVACIONAIS com ou sem ECAs

tabela de conteúdos ↟

Cirurgia, Ortopedia & MFR

✔ No increased risk of nonunion w/ bisphosphonate following operatively treated long-bone fractures | JBJS

Doente crítico/urgente

✔✔✔ The efficacy of prehospital IV fluid management in severely injured adult trauma patients | CJEM

Geral, Geriatria & Paliativos

✔ National Trends and Outcomes of More Frequent Than Guideline Recommended PSA Screening | Urology

Association Between Daily Alcohol Intake and Risk of All-Cause Mortality | JAMA Network Open

Infecciologia, Microbiologia & Antimicrobianos

High-flow nasal cannula reduces intubation rate in patients with COVID-19 with acute respiratory failure | BMJ Open

Oncologia

✔ Association Between 5α-Reductase Inhibitors and Prostate Cancer Mortality | JAMA Oncology

The effect of gastrointestinal microbiome supplementation on immune checkpoint inhibitor immunotherapy | JCRCO

Técnicas, POCUS, Exames & Outros

✔✔✔ Test characteristics of ultrasound for peritonsillar abscess: systematic review and meta-analysis | AEM

Diagnostic yield of CT head in delirium and altered mental status | JAGS

PRIMÁRIOS - SUB-ANÁLISE / COORTE / CASO-CONTROLO / INQUÉRITOS / A. ECONÓMICAS

tabela de conteúdos ↟

Cardiovascular

✔✔✔ Aspirin vs Clopidogrel for Long-Term Maintenance Monotherapy After PCI: HOST-EXAM Extended | Circulation

✔✔✔ Statins and diabetes before and after applying a novel technique to control for selection bias | AJMS

✔ Specialist consultation on ED revisits among uncomplicated recent-onset atrial fibrillation or flutter | CJEM

✔ Prolonged Moderate-Intensity Exercise Does Not Increase Muscle Injury in Statin Users | JACC

Oesophageal fistula following AF catheter ablation: The POTTER-AF study | EHJ

Cirurgia, Ortopedia & MFR

✔ Estimated Effect of Parathyroidectomy on Long-Term Kidney Function in Adults w/ Primary Hyperparathyroidism|AIM

Doente crítico/urgente

✔✔✔ Volume of fluid resuscitation and mortality modified by disease severity in patients with sepsis in ICU | BMJ Open

✔✔✔ Survival by Time-to-Administration of Amiodarone, Lidocaine, or Placebo in Shock-Refractory OHCA | AEM

✔ Prehospital Triage of Adults w/ Traumatic Injuries Following Implementation of Trauma Triage Intervention|JAMA NO

An observation-first strategy for liver injuries with “blush” on computed tomography is safe and effective | TACS

Gastroenterologia & Hepatologia

✔ Mortality After Postcolonoscopy Colorectal Cancer in the Veterans Affairs Health Care System | JAMA Network Open

Geral, Geriatria & Paliativos

Perspectives of Patients About Immediate Access to Test Results Through an Online Patient Portal|JAMANetworkOpen

Association of daily step patterns with mortality in US adults | JAMA Network Open

Use and Outcomes of Colonoscopy in Individuals Older Than 75 Years | JAMA Internal Medicine's Less is more

Infecciologia, Microbiologia & Antimicrobianos

✔ Risk of Death in Patients Hospitalized for COVID-19 vs Seasonal Influenza in Fall-Winter 2022-2023 | JAMA

Post-treatment outcomes of ceftriaxone vs antistaph penicillins or cefazolin for MSSA bacteremia | EJCMID

Comparative effectiveness of β-lactams for empirical treatment of MSSA bacteraemia | JAC

Meta-investigação & MBE

✔ Comparison of Availability of Trial Results in ClinicalTrials.gov and PubMed by Data Source and Funder Type | JAMA

✔ Statistical and Numerical Errors Made by the US CDC and Prevention During the COVID-19 Pandemic | SSRN

✔ COI among ID Clinical Practice Guideline Authors and the Pharmaceutical Industry | JAMA Network Open

Oncologia

✔ The response rate by tumour type for tissue-agnostic approved drugs | EJC

CASOS CLÍNICOS E SÉRIES

tabela de conteúdos ↟

Cardiovascular

Chest Pain, Paced Rhythm, and 2 Missed Indications for Emergent Reperfusion | JAMA Internal Medicine

An Unusual Cause of ST-Segment Elevation in the Right Precordial Leads—A Clue From the Humble Waves | JAMA IM

Dermatologia

Nonhealing Cutaneous Ulcers in a Patient With Myelodysplastic Syndrome | JAMA Oncology

Gastroenterologia & Hepatologia

An Unusual Cause of Acute Abdominal Pain: A Case Report and Review of the Diagnostic Reasoning | AIM

Hematologia

Systemic Amyloidosis: Is It ATTR or AL? | AJM

Abdominal Pain and Petechial Rash in a 95-Year-Old Farmer | JAMA

Imuno-mediadas

✔ Daratumumab for a Patient With Refractory Antineutrophil Cytoplasmatic Antibody–Associated Vasculitis | JAMA IM

Neurologia

Weakness and Paraparesis: A Common Presentation of the Rare Retrovirus HTLV | AMP

Lentiform Fork Sign on Magnetic Resonance Imaging After Methamphetamine and Alcohol Misuse | JAMA Neurology

Técnicas, POCUS, Exames & Outros

✔✔✔ Needle Guide for Real-Time US-Directed Aspiration of Peritonsillar Abscess in the ED: A Case Series | TJEM

Ultrasonography of Muscle Vibration Caused by MYBPC1 Variant | JAMA Neurology

OPINIÃO

PERSPECTIVA

tabela de conteúdos ↟

Cardiovascular

✔ Actually, Hyperacute T Waves Can Help Identify Occlusion MI | AEM

Doente crítico/urgente

✔ To View or Not To View? Standard Geometry Video Laryngoscopes and Screen Visualization | AEM

Geral, Geriatria & Paliativos

✔ What is the Future of Preprint Peer Review? | AMP

✔ Negative Secular Trends in Medicine: Part X:The Dumbing Down of America | AJM

FDA Green-lights First Over-the-counter Naloxone Spray | JAMA

Pandemia, Saúde e Proteção: O Que nos Diz o Health at a Glance 2022? | AMP

Hematologia

What a Study of Hibernating Bears Tells Us About Deep Vein Thrombosis | JAMA

Infecciologia, Microbiologia & Antimicrobianos

✔ The Use of Urinalysis and Urine Culture in Diagnosis: The Role of Uncertainty Tolerance | AJM

✔ When Oral Therapy Can Replace Intravenous Antibiotics—Changing Practice as New Data Emerge | JAMA IM

Meta-investigação & MBE

✔✔✔ 17y for Evidence to Change Practice - Field of Implementation Science Seeks to Speed Things Up | JAMA

Drug Repurposing and Observational Studies: The Case of Antivirals for the Treatment of COVID-19 | AIM

Neurologia

Challenges and Opportunities for the Promising Biomarker Blood Neurofilament Light Chain | JAMA Neurology

Incorporating the Central Vein Sign Into the Diagnostic Criteria for Multiple Sclerosis | JAMA Neurology

Nondrug Interventions for Dementia Improved Life, Reduced Costs | JAMA

✔✔✔ FOAMed

tabela de conteúdos ↟

Cardiovascular

#390 Resistant Hypertension | Curbsiders

Doente crítico/urgente

EMCrit 345 – I Guess We Need to Talk about CLOVERS and Fluids in Sepsis (Hopefully for the Last Time Ever)

Geral, Geriatria & Paliativos

EMCrit 346 – COMMS Lab – Resus Communication with Hayden Richards

ISBE & Cochrane Portugal Newsletter nº 238: Intervenções preventivas de quedas em idosos em ambulatório

#389 SHM #Converge2023 Recap | Curbsiders

Hematologia

91 Hypercoagulable Work-Up with Dr. Jean Connors | Curbsiders

Infecciologia, Microbiologia & Antimicrobianos

Steroids for pneumonia (CAPE COD and ESCAPe) | First10EM

#337 Clear, not cloudy: Antibiotic options for uncomplicated urinary tract infections - Tools for practice

Nefrologia

MMF in IgA: Inching into the MAINstream? | NephJC

Urinary anion gap doesn't work | Precious bodily fluids

Neurologia

Red Flag Headaches: General Approach and Cervical Artery Dissections - EMC

Cerebral Venous Thrombosis, Idiopathic Intracranial Hypertension, Giant Cell Arteritis and Peripartum Headache - EMC

Técnicas, POCUS, Exames & Outros

CJEM Visual Abstract – Just the facts: POCUS assessment for deep vein thrombosis

EMCrit 347 – How to Teach & Learn Laryngoscopy

Training for HALO procedures | St.Emlyn's

EMCrit 343 – CV-EMCrit: Who to Refer for VV ECMO – Patient Selection and When to Call for Help - EMCrit

---

ARA - Aumento de Risco Absoluto | ECA - Ensaio clínico aleatorizado | ITA - Intention-to-treat Analysis | MA - Meta-análise | MBE - Medicina baseada na evidência | NIT - Non-inferiority trial | NNH - Number needed to harm | NNT - Number needed to treat | PPA - Per protocol analysis | RRA - Redução do Risco Absoluto | RS - Revisão Sistemática